EP 1639371 A1 20060329 - METHODS FOR IDENTIFYING AGENTS, WHICH REGULATE CYTOKINES
Title (en)
METHODS FOR IDENTIFYING AGENTS, WHICH REGULATE CYTOKINES
Title (de)
VERFAHREN ZUR IDENTIFIZIERUNG VON AGENTIEN, DIE ZYTOKINE REGULIEREN
Title (fr)
PROCEDES POUR IDENTIFIER DES AGENTS REGULANT LES CYTOKINES
Publication
Application
Priority
- SE 2004001039 W 20040628
- SE 0301917 A 20030630
- US 49700303 P 20030820
Abstract (en)
[origin: WO2005001478A1] The present invention relates to methods for identifying agents that modulate the effect of cytokine class I receptor binding compounds, by inhibiting the interaction between the cytokine class I receptor and nuclear factors. The agents are useful for decreasing IGF-1 levels in a cell, and for the treatment of medical disorders caused by hormone dysregulation, such as growth hormone or prolactin dysregulation.
IPC 1-7
G01N 33/569; G01N 33/68; G01N 33/574; C12Q 1/68; A61K 38/30; C07K 16/24; C12N 15/18
IPC 8 full level
C07K 16/28 (2006.01); C12N 15/18 (2006.01); G01N 33/68 (2006.01); G01N 33/74 (2006.01)
CPC (source: EP)
A61P 43/00 (2017.12); C07K 16/2869 (2013.01); G01N 33/6863 (2013.01); G01N 33/74 (2013.01); G01N 2500/00 (2013.01)
Citation (search report)
See references of WO 2005001478A1
Citation (examination)
- LIU NIANDONG ET AL: "Mode of the autocrine/paracrine mechanism of growth hormone action", EXPERIMENTAL CELL RESEARCH, vol. 237, no. 1, 25 November 1997 (1997-11-25), pages 196 - 206
- TAO ZHU ET AL: "Signal transduction via the growth hormone receptor", CELLULAR SIGNALLING, vol. 13, September 2001 (2001-09-01), pages 599 - 616
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2005001478 A1 20050106; AU 2004252395 A1 20050106; CA 2528281 A1 20050106; EP 1639371 A1 20060329; JP 2007527513 A 20070927
DOCDB simple family (application)
SE 2004001039 W 20040628; AU 2004252395 A 20040628; CA 2528281 A 20040628; EP 04749077 A 20040628; JP 2006518583 A 20040628