EP 1648488 A4 20070124 - HUMAN MAST CELL-EXPRESSED MEMBRANE PROTEIN
Title (en)
HUMAN MAST CELL-EXPRESSED MEMBRANE PROTEIN
Title (de)
IN MENSCHLICHEN MASTZELLEN EXPRIMIERTES MEMBRANPROTEIN
Title (fr)
PROTEINE MEMBRANAIRE EXPRIMEE DANS DES MASTOCYTES D'ORIGINE HUMAINE
Publication
Application
Priority
- US 2004020296 W 20040625
- US 48336003 P 20030627
Abstract (en)
[origin: WO2005010152A2] The present invention relates to GPR91, a purinergic receptor-like polypeptide, its expression in mast cells, and its use in the diagnosis and/or treatment of mast cell mediated diseases, including allergic and nonallergic asthma, chronic obstructive pulmonary disease (COPD), allergic rhinitis, anaphylaxis, allergic gastrointestinal disease, atopic dermatitis, rheumatoid arthritis, and other allergic, autoimmune and inflammatory diseases. The invention also includes methods of screening of agonists and/or antagonists of the GPR91 receptor.
IPC 8 full level
A61K 39/395 (2006.01); A61K 38/00 (2006.01); C07K 14/705 (2006.01); G01N 33/567 (2006.01)
IPC 8 main group level
C12N (2006.01)
CPC (source: EP)
A61P 1/04 (2017.12); A61P 1/16 (2017.12); A61P 3/10 (2017.12); A61P 5/14 (2017.12); A61P 7/00 (2017.12); A61P 7/04 (2017.12); A61P 7/06 (2017.12); A61P 9/00 (2017.12); A61P 11/00 (2017.12); A61P 11/02 (2017.12); A61P 11/06 (2017.12); A61P 13/12 (2017.12); A61P 15/08 (2017.12); A61P 17/00 (2017.12); A61P 17/04 (2017.12); A61P 17/06 (2017.12); A61P 17/10 (2017.12); A61P 19/02 (2017.12); A61P 25/00 (2017.12); A61P 27/02 (2017.12); A61P 29/00 (2017.12); A61P 31/04 (2017.12); A61P 31/14 (2017.12); A61P 31/18 (2017.12); A61P 31/20 (2017.12); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 37/02 (2017.12); A61P 37/06 (2017.12); A61P 37/08 (2017.12); A61P 43/00 (2017.12); C07K 14/705 (2013.01); A61K 2039/505 (2013.01)
Citation (search report)
- [E] WO 2005050220 A1 20050602 - BAYER HEALTHCARE AG [DE], et al
- [X] WO 0198351 A2 20011227 - INCYTE GENOMICS INC [US], et al
- [X] US 2002137887 A1 20020926 - HEDRICK JOSEPH A [US], et al
- [A] YANG J ET AL: "Calcineurin/nuclear factors of activated T cells (NFAT)-activating and immunoreceptor tyrosine-based activation motif (ITAM)-containing protein (CNAIP), a novel ITAM-containing protein that activates the calcineurin/NFAT-signaling pathway", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM,, US, vol. 278, no. 19, 9 May 2003 (2003-05-09), pages 16797 - 16801, XP002273544, ISSN: 0021-9258
- See references of WO 2005010152A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2005010152 A2 20050203; WO 2005010152 A3 20050512; AU 2004259399 A1 20050203; CA 2531073 A1 20050203; CN 1812803 A 20060802; EP 1648488 A2 20060426; EP 1648488 A4 20070124; JP 2007526747 A 20070920
DOCDB simple family (application)
US 2004020296 W 20040625; AU 2004259399 A 20040625; CA 2531073 A 20040625; CN 200480017953 A 20040625; EP 04777035 A 20040625; JP 2006517621 A 20040625