EP 1648514 A2 20060426 - A METHOD OF PRE-SENSITIZING CANCER PRIOR TO TREATMENT WITH RADIATION AND/OR CHEMOTHERAPY AND A NOVEL CYTOKINE MIXTURE
Title (en)
A METHOD OF PRE-SENSITIZING CANCER PRIOR TO TREATMENT WITH RADIATION AND/OR CHEMOTHERAPY AND A NOVEL CYTOKINE MIXTURE
Title (de)
VERFAHREN ZUR VORSENSIBILISIERUNG VON KREBS VOR BEHANDLUNG MIT STRAHLUNG UND/ODER CHEMOTHERAPIE UND NEUES ZYTOKIN-GEMISCH
Title (fr)
METHODE DE SENSIBILISATION D'UN CANCER AVANT RADIOTHERAPIE ET/OU CHIMIOTHERAPIE ET NOUVEAU MELANGE DE CYTOKINE
Publication
Application
Priority
- US 2004020998 W 20040701
- US 61191403 A 20030703
Abstract (en)
[origin: US2005002896A1] This invention relates to a breakthrough method for pre-sensitizing cancer prior to a therapeutic treatment such as chemotherapy, radiation therapy or immuno-therapy and a novel cytokine mixture used in the method thereof. The cytokine mixture is a serum-free and mitogen-free mixture comprised of specific ratios of cytokines such as IL-1beta, TNF-alpha, IFN-gamma and GM-CSF to Interleukin 2 (IL-2), which is effective in inducing cancerous cells to enter a proliferative cell cycle phase thereby increasing their vulnerability to chemotherapy, radiation therapy and immuno-therapy. One such novel cytokine mixture is Multikine(R), which can be used alone or in combination with other drugs for the treatment of cancer thereby increasing the success of cancer treatment and the disease free survival of cancer patients.
IPC 1-7
IPC 8 full level
A61K 38/19 (2006.01); A61K 38/20 (2006.01); A61K 38/21 (2006.01); A61K 45/00 (2006.01)
IPC 8 main group level
A61K (2006.01)
CPC (source: EP US)
A61K 38/191 (2013.01 - EP US); A61K 38/193 (2013.01 - EP US); A61K 38/2006 (2013.01 - EP US); A61K 38/2013 (2013.01 - EP US); A61K 38/217 (2013.01 - EP US); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Citation (search report)
See references of WO 2005007086A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
US 2005002896 A1 20050106; US 6896879 B2 20050524; AU 2004257601 A1 20050127; CA 2531322 A1 20050127; CN 1845757 A 20061011; CN 1845757 B 20110525; EP 1648514 A2 20060426; JP 2007524634 A 20070830; US 2005158275 A1 20050721; US 2005163749 A1 20050728; WO 2005007086 A2 20050127; WO 2005007086 A3 20050707
DOCDB simple family (application)
US 61191403 A 20030703; AU 2004257601 A 20040701; CA 2531322 A 20040701; CN 200480025403 A 20040701; EP 04777305 A 20040701; JP 2006517794 A 20040701; US 2004020998 W 20040701; US 3383405 A 20050113; US 3383505 A 20050113