EP 1649001 A2 20060426 - ANTIBODIES AND USES THEREOF
Title (en)
ANTIBODIES AND USES THEREOF
Title (de)
ANTIKÖRPER UND DEREN VERWENDUNGEN
Title (fr)
ANTICORPS ET UTILISATIONS DE CEUX-CI
Publication
Application
Priority
- US 2004021002 W 20040630
- US 61123803 A 20030630
Abstract (en)
[origin: WO2005010153A2] The present invention provides antibodies or fragments thereof that bind to cancer cells and is important in physiological phenomena, such as cell rolling and metastasis. Therapeutic and diagnostic methods and compositions using such antibody fragments thereof are also provided. The methods and compositions according to the present invention can be used in targeting therapeutic agents and in diagnosis, prognosis, and staging of and therapy for such diseases as cancer, including tumor growth and metastasis, leukemia, auto-immune disease, and inflammatory disease. Also provided is a library of immunoglobulin binding domains having a diverse antigen-binding domain for complementary binding, wherein the library has diversity only in heavy chain CDR3.
IPC 1-7
IPC 8 full level
A61K 38/00 (2006.01); A61K 38/04 (2006.01); A61K 38/12 (2006.01); C07K 1/00 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01); C12N 5/07 (2010.01); C12N 5/078 (2010.01); C12N 5/09 (2010.01); C12P 21/08 (2006.01)
CPC (source: EP KR)
A61P 7/02 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 31/00 (2017.12 - EP); A61P 31/12 (2017.12 - EP); A61P 31/18 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 35/02 (2017.12 - EP); A61P 35/04 (2017.12 - EP); A61P 37/02 (2017.12 - EP); A61P 37/06 (2017.12 - EP); C07K 16/00 (2013.01 - KR); C07K 16/005 (2013.01 - EP); C07K 16/18 (2013.01 - KR); C07K 16/28 (2013.01 - KR); C07K 16/2866 (2013.01 - EP); C07K 16/2896 (2013.01 - EP); A61K 2039/505 (2013.01 - EP); C07K 2317/34 (2013.01 - EP); C07K 2317/565 (2013.01 - EP); C07K 2317/622 (2013.01 - EP); C07K 2317/73 (2013.01 - EP); C07K 2317/732 (2013.01 - EP); C07K 2319/00 (2013.01 - EP)
Citation (search report)
See references of WO 2005010153A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2005010153 A2 20050203; WO 2005010153 A3 20080313; AU 2004259406 A1 20050203; BR PI0411945 A 20061024; CA 2536644 A1 20050203; CN 101300021 A 20081105; EP 1649001 A2 20060426; IL 172510 A0 20060410; JP 2007528711 A 20071018; KR 20060106631 A 20061012; MX PA06000252 A 20061215; RU 2006102570 A 20070820
DOCDB simple family (application)
US 2004021002 W 20040630; AU 2004259406 A 20040630; BR PI0411945 A 20040630; CA 2536644 A 20040630; CN 200480024914 A 20040630; EP 04777308 A 20040630; IL 17251005 A 20051212; JP 2006518730 A 20040630; KR 20057025517 A 20051230; MX PA06000252 A 20040630; RU 2006102570 A 20040630