EP 1653977 A2 20060510 - TREATMENT OF DISORDERS ASSOCIATED WITH NATURAL KILLER T CELLS
Title (en)
TREATMENT OF DISORDERS ASSOCIATED WITH NATURAL KILLER T CELLS
Title (de)
BEHANDLUNG VON ERKRANKUNGEN IM ZUSAMMENHANG MIT NATÜRLICHEN KILLER-T-ZELLEN
Title (fr)
PROCEDES ET COMPOSITIONS DE TRAITEMENT DE MALADIE ET DE TROUBLES ASSOCIES A DES LYMPHOCYTES TNK
Publication
Application
Priority
- US 2004022913 W 20040716
- US 48833903 P 20030717
Abstract (en)
[origin: WO2005014008A2] The invention relates to methods and compositions useful in the treatment of autoimmune disorders or diseases as well as disorders or diseases having an autoimmune component such as AIDS. Preferred methods and compositions of the invention comprise use of a Beta Galactosyl Ceramide compound to treat a mammal suffering from or susceptible to such disorders. Methods and compositions of the invention can reduce NKT cells effectively in vivo in the substantial absence of undesired bystander events (cellular activation, cytokine production, systemic inflammation, etc). Methods and compositions of the invention can also reduce tumor size or ability to metastasize.
IPC 1-7
A61K 31/7032; A61P 17/00; A61P 35/00; A61P 37/00; A61P 37/06; A61P 31/18
IPC 8 full level
A61K 31/7032 (2006.01)
CPC (source: EP)
A61K 31/7032 (2013.01); A61P 17/00 (2017.12); A61P 31/18 (2017.12); A61P 35/00 (2017.12); A61P 37/00 (2017.12); A61P 37/06 (2017.12)
Citation (search report)
See references of WO 2005014008A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2005014008 A2 20050217; WO 2005014008 A3 20051103; EP 1653977 A2 20060510
DOCDB simple family (application)
US 2004022913 W 20040716; EP 04778424 A 20040716