EP 1660523 A2 20060531 - INDUCTION OF ANTIVIRAL NEUTRALIZING ANTIBODIES IN HUMANS AND ANIMALS
Title (en)
INDUCTION OF ANTIVIRAL NEUTRALIZING ANTIBODIES IN HUMANS AND ANIMALS
Title (de)
INDUKTION ANTIVIRALER NEUTRALISIERENDER ANTIKÖRPER BEIM MENSCHEN UND BEIM TIER
Title (fr)
INDUCTION D'ANTICORPS NEUTRALISANTS ANTIVIRAUX CHEZ LES HOMMES ET LES ANIMAUX
Publication
Application
Priority
- DE 2004001897 W 20040826
- DE 10339966 A 20030826
- US 50069903 P 20030908
Abstract (en)
[origin: WO2005021574A2] The invention relates to immunogenic constructs that in principle comprise two different domains of the transmembrane envelope protein of enveloped viruses including retroviruses including HIV, a pharmaceutical agent for inducing humoral neutralizing immune responses to viral infections and to a kit for the detection of antibodies and viral antigens. The invention also relates to a method for inducing an antibody response and to a method for the passive immunization of an organism using neutralizing antibodies that were obtained using the above-mentioned immunogenic constructs. Finally, the invention relates to a bioassay for detecting viral infection and for detecting the production of neutralizing antibodies.
IPC 1-7
C07K 14/16; C07K 14/005; C07K 16/10; A61K 38/16; A61K 39/21; G01N 33/569; G01N 33/68; C12N 15/49; A61P 31/14
IPC 8 full level
A61K 39/21 (2006.01); C07K 14/005 (2006.01); C07K 14/16 (2006.01)
CPC (source: EP)
A61K 39/12 (2013.01); A61K 39/21 (2013.01); A61P 31/14 (2017.12); C07K 14/005 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55566 (2013.01); C12N 2740/16122 (2013.01); C12N 2740/16134 (2013.01)
Citation (search report)
See references of WO 2005021574A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2005021574 A2 20050310; WO 2005021574 A3 20051124; CA 2548483 A1 20050310; EP 1660523 A2 20060531
DOCDB simple family (application)
DE 2004001897 W 20040826; CA 2548483 A 20040826; EP 04786181 A 20040826