Global Patent Index - EP 1660658 A2

EP 1660658 A2 20060531 - THE USE OF SIRNA SILENCING IN THE PREVENTION OF METASTASIS

Title (en)

THE USE OF SIRNA SILENCING IN THE PREVENTION OF METASTASIS

Title (de)

VERWENDUNG VON SIRNA-SILENCING BEI DER PRÄVENTION DER METASTASE

Title (fr)

UTILISATION DU SILENCAGE SIRNA DANS LA PREVENTION DES METASTASES

Publication

EP 1660658 A2 20060531 (EN)

Application

EP 04816701 A 20040805

Priority

  • NO 2004000238 W 20040805
  • NO 20033492 A 20030806
  • US 49731403 P 20030825

Abstract (en)

[origin: WO2005040187A2] The present invention relates to synthesised RNAs, more specifically short interfering RNAs (siRNAs) that are able to modulate the expression of Tissue Factor (TF) and the use thereof in the prevention of metastasis and treatment of cancer.

IPC 1-7

C12N 15/11; A61K 31/713; C07H 21/00; A61P 35/04

IPC 8 full level

A61K 48/00 (2006.01); C07H 21/00 (2006.01); C12N 15/113 (2010.01); A61K 38/00 (2006.01)

CPC (source: EP)

A61P 9/14 (2017.12); A61P 35/04 (2017.12); A61P 43/00 (2017.12); C07H 21/00 (2013.01); C12N 15/1138 (2013.01); A61K 38/00 (2013.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01)

Citation (search report)

See references of WO 2005040187A2

Citation (examination)

  • AMARZGUIOUI M. ET AL: "Ex vivo and in vivo delivery of anti-tissue factor short interfering RNA inhibits mouse pulmonary metastasis of B16 melanoma cells", CLINICAL CANCER RESEARCH, vol. 12, July 2006 (2006-07-01), pages 4055 - 4061
  • Declaration of Pr. Inge Sandlie of the university of Oslo as filed with the letter of 10.08.2006.
  • BROMBERG M. ET AL: "Tissue factor promotes melanoma metastasis by a pathway independent of blood coagulation", PROC.NATL.ACAD.SCI., vol. 92, August 1995 (1995-08-01), pages 8205 - 8209

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2005040187 A2 20050506; WO 2005040187 A3 20050901; AU 2004284013 A1 20050506; CA 2534996 A1 20050506; EP 1660658 A2 20060531; JP 2007501225 A 20070125

DOCDB simple family (application)

NO 2004000238 W 20040805; AU 2004284013 A 20040805; CA 2534996 A 20040805; EP 04816701 A 20040805; JP 2006522519 A 20040805