Global Patent Index - EP 1663172 A1

EP 1663172 A1 20060607 - POLYSACCHARIDE DOUBLE-LAYER MICROCAPSULES AS CARRIERS FOR BIOLOGICALLY ACTIVE SUBSTANCE ORAL ADMINISTRATION

Title (en)

POLYSACCHARIDE DOUBLE-LAYER MICROCAPSULES AS CARRIERS FOR BIOLOGICALLY ACTIVE SUBSTANCE ORAL ADMINISTRATION

Title (de)

POLYSACCHARID-DOPPELSCHICHT-MIKROKAPSELN ALS TRÄGER FÜR BIOLOGISCHE WIRKSUBSTANZ ZUR ORALEN VERABREICHUNG

Title (fr)

MICROCAPSULES A DOUBLE COUCHE DE POLYSACCHARIDES UTILISEES EN TANT QU'EXCIPIENTS POUR L'ADMINISTRATION PAR VOIE ORALE DE SUBSTANCES BIOLOGIQUEMENT ACTIVES

Publication

EP 1663172 A1 20060607 (EN)

Application

EP 04766400 A 20040803

Priority

  • EP 2004051693 W 20040803
  • IT MI20031617 A 20030806

Abstract (en)

[origin: WO2005013941A1] The present invention relates to microcapsules with a double-layer of natural polysaccharides - chitosan and alginate - gelified and stabilized by means of a divalent ion containing inside at least one biologically active substance. The microcapsules of the invention can be employed as carriers for the oral administration of biologically active substances, also associated with an adjuvant of the biological response of the same, administered for a preventive or therapeutic purpose. These substances can be chosen, for example, from antigens and adjuvants, suitable for immune response stimulation against infective and non-infective agents, or from chemotherapeutics and adjuvants with therapeutic type effects. According to the type of biologically active substance encapsulated in the microcapsules, there can be a variety of uses for oral vaccination or therapy in the human and veterinary field.

IPC 1-7

A61K 9/48

IPC 8 full level

A61K 9/16 (2006.01)

CPC (source: EP US)

A61K 9/1652 (2013.01 - EP US)

Citation (search report)

See references of WO 2005013941A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2005013941 A1 20050217; AT E395909 T1 20080615; CA 2534368 A1 20050217; DE 602004013993 D1 20080703; EP 1663172 A1 20060607; EP 1663172 B1 20080521; IL 173481 A0 20060611; IL 173481 A 20100630; IT MI20031617 A1 20050207; US 2006228422 A1 20061012

DOCDB simple family (application)

EP 2004051693 W 20040803; AT 04766400 T 20040803; CA 2534368 A 20040803; DE 602004013993 T 20040803; EP 04766400 A 20040803; IL 17348104 A 20040803; IT MI20031617 A 20030806; US 56769904 A 20040803