EP 1663246 A2 20060607 - SCREENING METHOD BASED ON THE SGK GENE FAMILY AND GLUT1
Title (en)
SCREENING METHOD BASED ON THE SGK GENE FAMILY AND GLUT1
Title (de)
SCREENING VERFAHREN, BASIEREND AUF DER SGK-GENFAMILIE UND GLUT1
Title (fr)
METHODE DE SCREENING UTILISANT LA FAMILLE GENIQUE SGK ET GLUT1
Publication
Application
Priority
- EP 2004001048 W 20040205
- DE 10305212 A 20030207
Abstract (en)
[origin: WO2004069258A2] The invention relates to the use of a functional inhibitor of hsgk1or hsgk3 protein or a negative transcription regulator of the hsgk1 or hsgk3 gene in the production of a medicament for the treatment and/or prophylaxis of a cataract, glaucoma or diabetic neuropathy. Another aspect of the invention relates to the use of a single-stranded or double-stranded nucleic acid comprising the hsgk1 sequence according to Acc No. NM 005627 or one of the fragments thereof or comprising the hsgk3 sequence according to Acc. No. AF169035 or one of the fragments thereof in the diagnosis of a predisposition to the formation of a cataract, glaucoma and/or diabetic neuropathy, in addition to a kit for diagnosis of a predisposition to the formation of a cataract, glaucoma and/or diabetic neuropathy, comprising the above-mentioned nucleic acid. The invention further relates to various screening methods for identifying and characterizing therapeutically effective substances from a plurality of test substances for the treatment and/or prophylaxis of at least one disease selected from cataracts, glaucoma or diabetic neuropathy.
IPC 1-7
A61K 31/55; A61K 31/4355; A61P 27/06; A61P 27/12; A61P 25/02; A61K 31/00; A61K 31/713; A61K 31/711; A61K 31/395; G01N 33/50
IPC 8 full level
G01N 33/50 (2006.01); A61K 31/00 (2006.01); A61K 31/395 (2006.01); A61K 31/4355 (2006.01); A61K 31/55 (2006.01); A61K 31/711 (2006.01); A61K 31/713 (2006.01); A61P 25/02 (2006.01); A61P 27/06 (2006.01); A61P 27/12 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP KR US)
A61K 31/00 (2013.01 - EP); A61K 31/395 (2013.01 - EP US); A61K 31/4355 (2013.01 - EP); A61K 31/55 (2013.01 - EP); A61K 31/711 (2013.01 - EP); A61K 31/713 (2013.01 - EP); A61K 38/16 (2013.01 - KR); A61K 38/17 (2013.01 - KR); A61K 48/00 (2013.01 - KR); A61P 25/02 (2017.12 - EP); A61P 27/00 (2017.12 - EP); A61P 27/06 (2017.12 - EP); A61P 27/12 (2017.12 - EP); A61P 43/00 (2017.12 - EP); G01N 33/6893 (2013.01 - EP); G01N 2800/166 (2013.01 - EP); G01N 2800/168 (2013.01 - EP)
Citation (search report)
See references of WO 2004069258A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated extension state (EPC)
LT LV
DOCDB simple family (publication)
WO 2004069258 A2 20040819; WO 2004069258 A3 20050224; AU 2004210416 A1 20040819; BR PI0407300 A 20060207; CA 2514703 A1 20040819; CN 1771039 A 20060510; DE 10305212 A1 20040819; EP 1663246 A2 20060607; JP 2006519189 A 20060824; KR 20050114214 A 20051205; MX PA05008394 A 20051005; PL 378399 A1 20060403; RU 2005127808 A 20060527; ZA 200506280 B 20060531
DOCDB simple family (application)
EP 2004001048 W 20040205; AU 2004210416 A 20040205; BR PI0407300 A 20040205; CA 2514703 A 20040205; CN 200480007034 A 20040205; DE 10305212 A 20030207; EP 04708350 A 20040205; JP 2006501737 A 20040205; KR 20057014582 A 20050808; MX PA05008394 A 20040205; PL 37839904 A 20040205; RU 2005127808 A 20040205; ZA 200506280 A 20050805