EP 1664055 B9 20071010 - 9-AMINO-PODOPHYLLOTOXIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES
Title (en)
9-AMINO-PODOPHYLLOTOXIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES
Title (de)
9-AMINOPODOPHYLLOTOXINDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND PHARMAZEUTISCHE ZUSAMMENSETZUNGEN, DIE DIESE DERIVATE ENTHALTEN
Title (fr)
DERIVES DE 9-AMINO-PODOPHYLLOTOXINE, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT
Publication
Application
Priority
- FR 2004002218 W 20040901
- FR 0310367 A 20030902
Abstract (en)
[origin: WO2005023817A1] The invention relates to compounds of formula (I), wherein R1 is a group selected from hydrogen, alkyl, aryl, aryalkil, heteroaryl, heteroarylalkyl, alkylcarbonyl, arylcarbonyl, arylalkylcarbonyl, alkoxycarbonyl, aryloxycarbonyl, arylalkoxycarbonyl, heterocycloalkoxycarbonyl, alkylsulfonyl, arylsulfonyl, arylalkylsulfonyl, phosphonic and Si(Ra)2Rb, Y is a group selected from HN-NH and N-R2, R3 is a hydrogen atom, an alkyl, cycloalkyl, aryl, arylalkyl group, R4 is hydrogen atom or an alkyl group, enantiomers, diastereoisomers and the salts thereof.
IPC 8 full level
C07D 493/04 (2006.01); A61K 31/36 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP US)
A61P 35/00 (2018.01 - EP); C07D 493/04 (2013.01 - EP US)
Designated contracting state (EPC)
CH DE FR GB LI
DOCDB simple family (publication)
FR 2859208 A1 20050304; FR 2859208 B1 20060121; AR 045549 A1 20051102; CA 2546823 A1 20050317; DE 602004003719 D1 20070125; DE 602004003719 T2 20071018; EP 1664055 A1 20060607; EP 1664055 B1 20061213; EP 1664055 B9 20071010; US 2006247246 A1 20061102; US 7378419 B2 20080527; WO 2005023817 A1 20050317
DOCDB simple family (application)
FR 0310367 A 20030902; AR P040103129 A 20040901; CA 2546823 A 20040901; DE 602004003719 T 20040901; EP 04787274 A 20040901; FR 2004002218 W 20040901; US 57620106 A 20060417