Title (en)

STRUCTURE BASED AND COMBINATORIALLY SELECTED OLIGONUCLEOSIDE PHOSPHOROTHIOATE AND PHOSPHORODITHIOATE APTAMER TARGETING AP-1 TRANSCRIPTION FACTORS

Title (de)

STRUKTURBASIERTE UND KOMBINATORISCH AUSGEWÄHLTE OLIGONUCLEOSID-PHOSPHOROTHIOAT UND PHOSPHORODITHIOAT APTAMER TARGETING AP-1 TRANSKRIPTIONSFAKTOREN

Title (fr)

APTAMERE A OLIGONUCLEOSIDE PHOSPHOROTHIOATE ET PHOSPHORODITHIOATE SELECTIONNE DE MANIERE COMBINATOIRE ET SELON LA STRUCTURE POUR LE CIBLAGE DES FACTEURS DE TRANSCRIPTION AP-1

Publication

EP 1667729 A2 20060614 (EN)

Application

EP 04776088 A 20040520

Priority

• US 2004016246 W 20040520
• US 47288803 P 20030523

Abstract (en)

[origin: WO2005018537A2] The present invention includes composition and methods for making and using a combinatorial library to identify modified thioaptamers that bind to, and affect the innune response of a host animal, transcription factors such as IL-6, NF-kB, AP-1 and the like. Composition and methods are also provided for the treatment of viral infections, as well as, vaccines and vaccine adjuvants are provided that modify host immune responses.

IPC 1-7

A61K 48/00

IPC 8 full level

A61K 48/00 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); C12N 15/115 (2010.01)

IPC 8 main group level

A61K (2006.01)

CPC (source: EP)

C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 15/115 (2013.01); A61K 2039/55561 (2013.01); C12N 2310/13 (2013.01); C12N 2310/16 (2013.01); C12N 2310/315 (2013.01); C12N 2310/51 (2013.01); C12N 2320/11 (2013.01); C12N 2330/31 (2013.01); C12N 2760/12211 (2013.01); Y02A 50/30 (2018.01)

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2005018537 A2 20050303; WO 2005018537 A3 20050526; CA 2526853 A1 20050303; EP 1667729 A2 20060614; EP 1667729 A4 20071017

DOCDB simple family (application)

US 2004016246 W 20040520; CA 2526853 A 20040520; EP 04776088 A 20040520