EP 1670422 A2 20060621 - IDENTIFICATION OF KINASE INHIBITORS
Title (en)
IDENTIFICATION OF KINASE INHIBITORS
Title (de)
IDENTIFIZIERUNG VON KINASE-INHIBITOREN
Title (fr)
IDENTIFICATION D'INHIBITEURS DE KINASE
Publication
Application
Priority
US 0329870 W 20030917
Abstract (en)
[origin: WO2005034840A2] The invention concerns the identification of protein kinase inhibitors that preferentially bind to the inactive conformation of a target protein kinase. The inhibitors are identified by locking the target protein kinase in an inactive conformation, and using Tethering to identify inhibitors preferentially targeting the inactive conformation.
IPC 1-7
IPC 8 full level
C12Q 1/48 (2006.01); G01N 33/566 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP)
C12Q 1/485 (2013.01); G01N 33/6815 (2013.01); G01N 33/6842 (2013.01); G01N 2333/912 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated extension state (EPC)
AL LT LV MK
DOCDB simple family (publication)
WO 2005034840 A2 20050421; WO 2005034840 A3 20061005; WO 2005034840 A8 20060420; AU 2003270848 A1 20050427; CA 2539064 A1 20050421; EP 1670422 A2 20060621; EP 1670422 A4 20070801
DOCDB simple family (application)
US 0329870 W 20030917; AU 2003270848 A 20030917; CA 2539064 A 20030917; EP 03752561 A 20030917