EP 1670814 A1 20060621 - AMIDOMETHYL SUBSTITUTED 1-(CARBOXYALKYL)-CYCLOPENTYLCARBONYLAMINO-BENZAZEPINE-N-ACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS
Title (en)
AMIDOMETHYL SUBSTITUTED 1-(CARBOXYALKYL)-CYCLOPENTYLCARBONYLAMINO-BENZAZEPINE-N-ACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS
Title (de)
AMIDOMETHYLSUBSTITUIERTE 1-(CARBOXYALKYL)-CYCLOPENTYLCARBONYLAMINOBENZAZEPIN-N-ESSIGSÄUREDERIVATE, VERFAHREN UND ZWISCHENPRODUKTE ZU DEREN HERSTELLUNG UND MEDIKAMENTE, DIE DIESE VERBINDUNGEN ENTHALTEN
Title (fr)
DERIVES D'ACIDE 1-(CARBOXYALKYL)-CYCLOPENTYLCARBONYLAMINO-BENZAZEPINE-N-ACETIQUE A SUBSTITUTION AMIDOMETHYLE, PROCEDE POUR LES PREPARER ET MEDICAMENTS CONTENANT CES COMPOSES
Publication
Application
Priority
- EP 2004052289 W 20040923
- DE 10344848 A 20030926
- EP 04100065 A 20040112
- EP 04766846 A 20040923
Abstract (en)
[origin: WO2005030795A1] Described are novel compounds with neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity of the general formula (I), wherein the substituents R<1>, R<2> , R<3> and R<4> have the meanings given in the description and also medicaments containing these compounds, in particular medicaments suitable for treating or preventing cardiovascular diseases, sexual dysfunction and/or adverse conditions associated with apoptosis.
IPC 1-7
IPC 8 full level
A61P 9/12 (2006.01); C07K 5/02 (2006.01); C07K 5/078 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP KR)
A61K 38/00 (2013.01 - KR); A61K 38/05 (2013.01 - KR); A61P 1/04 (2017.12 - EP); A61P 1/16 (2017.12 - EP); A61P 1/18 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 5/18 (2017.12 - EP); A61P 7/06 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/04 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 13/12 (2017.12 - EP); A61P 15/00 (2017.12 - EP); A61P 15/08 (2017.12 - EP); A61P 15/10 (2017.12 - EP); A61P 17/00 (2017.12 - EP); A61P 17/02 (2017.12 - EP); A61P 17/06 (2017.12 - EP); A61P 17/14 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/08 (2017.12 - EP); A61P 25/14 (2017.12 - EP); A61P 25/16 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 27/16 (2017.12 - EP); A61P 31/04 (2017.12 - EP); A61P 31/10 (2017.12 - EP); A61P 31/12 (2017.12 - EP); A61P 37/02 (2017.12 - EP); A61P 37/06 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07K 5/02 (2013.01 - KR); C07K 5/0222 (2013.01 - EP); C07K 5/06139 (2013.01 - EP KR); A61K 38/00 (2013.01 - EP); Y02A 50/30 (2017.12 - EP)
Citation (search report)
See references of WO 2005030795A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2005030795 A1 20050407; AR 045798 A1 20051116; AU 2004276002 A1 20050407; AU 2004276002 B2 20100722; BR PI0414744 A 20061121; CA 2539895 A1 20050407; EP 1670814 A1 20060621; HK 1096105 A1 20070525; IL 174373 A0 20060801; IL 174373 A 20111229; JP 2007535482 A 20071206; JP 4824562 B2 20111130; KR 101264934 B1 20130520; KR 20060101460 A 20060925; MX PA06003226 A 20060522; NO 20061821 L 20060622; RU 2006113946 A 20071110; RU 2368601 C2 20090927; SA 04250283 B1 20080526; TW 200524874 A 20050801; TW I332947 B 20101111
DOCDB simple family (application)
EP 2004052289 W 20040923; AR P040103409 A 20040922; AU 2004276002 A 20040923; BR PI0414744 A 20040923; CA 2539895 A 20040923; EP 04766846 A 20040923; HK 07103455 A 20070330; IL 17437306 A 20060316; JP 2006527420 A 20040923; KR 20067005869 A 20060324; MX PA06003226 A 20040923; NO 20061821 A 20060425; RU 2006113946 A 20040923; SA 04250283 A 20040912; TW 93128652 A 20040922