EP 1675943 A2 20060705 - NANOLITER-SCALE SYNTHESIS OF ARRAYED BIOMATERIALS AND SCREENING THEREOF
Title (en)
NANOLITER-SCALE SYNTHESIS OF ARRAYED BIOMATERIALS AND SCREENING THEREOF
Title (de)
SYNTHESE VON IN EINEM ARRAY ANGEORDNETEN BIOMATERIALIEN IM NANOLITERMASSSTAB UND SCREENING DAVON
Title (fr)
SYNTHESE, A L'ECHELLE DU NANOLITRE, DE BIOMATERIAUX EN RESEAUX ET CRIBLAGE DE CEUX-CI
Publication
Application
Priority
- US 2004030095 W 20040915
- US 50316503 P 20030915
- US 57018704 P 20040512
- US 84370704 A 20040512
Abstract (en)
[origin: WO2005028619A2] A population of embryonic epithelial cells produced in vitro from embryonic stem cells. In one embodiment, at least 45% of the cells express cytokeratin, for example, cytokeratin-7. A method of screening cell-polymer interactions. The method includes depositing monomers as a plurality of discrete elements on a substrate, causing the deposited monomers to polymerize, thereby creating an array of discrete polymer elements on the substrate, incubating the substrate in a cell-containing culture medium, and characterizing a predetermined cell behavior on each polymer element.
IPC 1-7
IPC 8 full level
C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12N 5/071 (2010.01); G01N 33/50 (2006.01)
IPC 8 main group level
C12N (2006.01)
CPC (source: EP)
C12N 5/0606 (2013.01); G01N 33/5073 (2013.01); C12N 2503/02 (2013.01); C12N 2533/30 (2013.01); G01N 2500/10 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2005028619 A2 20050331; WO 2005028619 A3 20050909; CA 2539670 A1 20050331; EP 1675943 A2 20060705; EP 1675943 A4 20071205
DOCDB simple family (application)
US 2004030095 W 20040915; CA 2539670 A 20040915; EP 04788758 A 20040915