EP 1685253 A2 20060802 - ADAPTER FOR COUPLING A SUBSTANCE WHICH IS TO BE COUPLED TO A CELL SURFACE
Title (en)
ADAPTER FOR COUPLING A SUBSTANCE WHICH IS TO BE COUPLED TO A CELL SURFACE
Title (de)
ADAPTER ZUM ANKOPPELN EINER AN EINER ZELLOBERFLÄCHE ANZUKOPPELNDEN SUBSTANZ
Title (fr)
ADAPTATEUR POUR COUPLER UNE SUBSTANCE A UNE SURFACE CELLULAIRE
Publication
Application
Priority
- EP 2004014419 W 20041217
- EP 03029139 A 20031218
- EP 04804022 A 20041217
Abstract (en)
[origin: EP1544305A1] Adapter (I) for coupling a substance (II) to the surface of a cell comprises: (a) a segment (Ia) that recognizes and binds to (II); and (b) a recombinant segment (Ib) for arranging (I) on the cell surface and having affinity for one or more negatively charged cell-surface structures. Independent claims are also included for: (1) nucleic acid (NA) including a sequence that encodes (I); (2) virus for expressing (I); (3) method for non-therapeutic coupling of (II) and (I); and (4) pharmaceutical for mediating and/or improving coupling of (II) to a cell comprising (I) and/or the virus of (2), plus a carrier.
IPC 8 full level
C12N 15/86 (2006.01); A61K 47/48 (2006.01); C12N 15/62 (2006.01)
CPC (source: EP)
A61K 47/6901 (2017.07); A61P 35/00 (2017.12); C12N 15/625 (2013.01)
Citation (search report)
See references of WO 2005059129A2
Citation (examination)
- WO 03050238 A2 20030619 - UNIV IOWA RES FOUND [US], et al
- WU HONGJU ET AL: "Double Modification of Adenovirus Fiber with RGD and Polylysine Motifs Improves Coxsackievirus-Adenovirus Receptor-Independent Gene Transfer Efficiency", HIUMAN GENE THERAPY, vol. 13, 1 September 2002 (2002-09-01), pages 1647 - 1653
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
EP 1544305 A1 20050622; EP 1685253 A2 20060802; JP 2007514429 A 20070607; WO 2005059129 A2 20050630; WO 2005059129 A3 20051006
DOCDB simple family (application)
EP 03029139 A 20031218; EP 04804022 A 20041217; EP 2004014419 W 20041217; JP 2006544360 A 20041217