Global Patent Index - EP 1693062 A2

EP 1693062 A2 20060823 - Androgen receptor-dependent gene expression control

Title (en)

Androgen receptor-dependent gene expression control

Title (de)

Kontrolle der Androgen-Receptor abhängigen Gen-Exprimierung

Title (fr)

Contrôle de l'expression génique dependante du recepteur d'androgène

Publication

EP 1693062 A2 20060823 (EN)

Application

EP 05015253 A 20050713

Priority

  • EP 05003596 A 20050218
  • EP 05015253 A 20050713

Abstract (en)

The invention relates to the use of at least one siRNA ("short interfering RNA") and/or at least one anti-LSD1 antibody for modulating the activity of the lysine-specific demethylase (LSD1) in a mammal or for the manufacture of a medicament for modulating the activity of the lysine-specific demethylase (LSD1) in a mammal. The invention also relates to a pharmaceutical composition for controlling the androgen receptor-dependent gene expression, comprising an effective dose of at least one siRNA and/or at least one anti-LSD1 antibody suitable for modulating the activity of the lysine-specific demethylase (LSD1) in a mammal. The invention also relates to a method for controlling the androgen receptor-dependent gene expression in a mammal, said process comprising the step of administering to said mammal, on a suitable route, an effective dose of a pharmaceutical composition modulating an activity of the lysine-specific demethylase (LSD1) in a mammal.

IPC 8 full level

A61K 31/7088 (2006.01); A61K 39/00 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01)

CPC (source: EP)

A61P 35/00 (2017.12); C12N 15/1137 (2013.01); C12N 2310/14 (2013.01)

Citation (applicant)

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Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

EP 1693062 A2 20060823; EP 1693062 A3 20071212

DOCDB simple family (application)

EP 05015253 A 20050713