EP 1694695 A4 20071031 - COMPLETE MITOCHONDRIAL GENOME SEQUENCES AS A DIAGNOSTIC TOOL FOR THE HEALTH SCIENCES
Title (en)
COMPLETE MITOCHONDRIAL GENOME SEQUENCES AS A DIAGNOSTIC TOOL FOR THE HEALTH SCIENCES
Title (de)
VOLLSTÄNDIGE MITOCHONDRIALE GENOMSEQUENZEN ALS DIAGNOSTISCHES TOOL FÜR DIE MEDIZINISCHEN WISSENSCHAFTEN
Title (fr)
SEQUENCES COMPLETES DU GENOME MITOCHONDRIAL UTILISEES COMME OUTIL DE DIAGNOSTIC POUR DES SCIENCES DE LA SANTE
Publication
Application
Priority
- CA 2004002124 W 20041213
- US 73237403 A 20031211
Abstract (en)
[origin: WO2005056573A1] The examination of mutations in the mitochondrial genome is used as a diagnostic system for diseases such as prostate cancer, and non melanoma skin cancer. Characteristic mutations and rearrangements including, point mutations (transitions, transversions), deletions, inversions, duplications, recombinations, insertions or combinations thereof in the mitochondrial genome are used as early indicators of prostate cancer, and non melanoma skin cancer. Moreover, the 4977 bp, or "common deletion" as well as other associated mutations and/or deletions are used as a measure of aging.
IPC 8 full level
C07H 21/04 (2006.01); C12Q 1/68 (2006.01); G06F 19/00 (2006.01); G06F 19/18 (2011.01); G16B 20/20 (2019.01); G16B 20/40 (2019.01)
CPC (source: EP US)
C12Q 1/6883 (2013.01 - EP); C12Q 1/6886 (2013.01 - EP); G16B 20/00 (2019.01 - EP); G16B 20/20 (2019.01 - EP US); G16B 20/40 (2019.01 - EP US); C12Q 2600/112 (2013.01 - EP); C12Q 2600/156 (2013.01 - EP); C12Q 2600/158 (2013.01 - EP)
Citation (search report)
- [X] WO 03078661 A1 20030925 - GYLLENSTEN ULF [SE], et al
- [X] DURHAM S E ET AL: "Mitochondrial DNA damage in non-melanoma skin cancer.", BRITISH JOURNAL OF CANCER 13 JAN 2003, vol. 88, no. 1, 13 January 2003 (2003-01-13), pages 90 - 95, XP002450141, ISSN: 0007-0920
- [A] KOGELNIK ANDREAS M ET AL: "MITOMAP: a human mitochondrial genome database-1998 update", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 26, no. 1, 1998, pages 112 - 115, XP002966479, ISSN: 0305-1048
- [T] BANDELT HANS-JÜRGEN ET AL: "What is a 'novel' mtDNA mutation--and does 'novelty' really matter?", JOURNAL OF HUMAN GENETICS 2006, vol. 51, no. 12, 2006, pages 1073 - 1082, XP002450142, ISSN: 1434-5161
- See references of WO 2005056573A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2005056573 A1 20050623; CA 2550135 A1 20050623; EP 1694695 A1 20060830; EP 1694695 A4 20071031
DOCDB simple family (application)
CA 2004002124 W 20041213; CA 2550135 A 20041213; EP 04802299 A 20041213