EP 1694838 A2 20060830 - RNA INTERFERENCE MEDIATED INHIBITION OF GPRA AND AAA1 GENE EXPRESSION USING SHORT NUCLEIC ACID (siNA)
Title (en)
RNA INTERFERENCE MEDIATED INHIBITION OF GPRA AND AAA1 GENE EXPRESSION USING SHORT NUCLEIC ACID (siNA)
Title (de)
RNA-INTERFERENZ-VERMITTELTE HEMMUNG DER GPRA- UND AAA1-GENEXPRESSION UNTER VERWENDUNG VON SINA (SHORT INTERFERING NUCLEIC ACID)
Title (fr)
INHIBITION PAR L'ARN INTERFERENCE DE L'EXPRESSION DES GENES GPRA ET AAA1 UTILISANT UN ACIDE NUCLEIQUE COURT
Publication
Application
Priority
- US 2004027231 W 20040820
- US 69305903 A 20031023
- US 72044803 A 20031124
- US 72778003 A 20031203
- US 75780304 A 20040114
- US 54348004 P 20040210
- US 78044704 A 20040213
- US 82696604 A 20040416
- US 2004013456 W 20040430
- US 57008604 P 20040511
- US 2004016390 W 20040524
Abstract (en)
[origin: WO2005045038A2] This invention relates to compounds, compositions, and methods useful for modulating G protein-coupled receptor for asthma susceptibility (GPRA) and asthma-associated alternatively spliced gene 1 (AAA1) gene expression using short interfering nucleic acid (siNA) molecules. This invention also relates to compounds, compositions, and methods useful for modulating the expression and activity of other genes involved in pathways of GPRA and/or AAA1 gene expression and/or activity by RNA interference (RNAi) using small nucleic acid molecules. In particular, the instant invention features small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules and methods used to modulate the expression of GPRA and/or AAA1 genes.
IPC 8 full level
C12N 15/113 (2010.01); C12N 15/87 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61K 49/0008 (2013.01); A61P 1/00 (2017.12); A61P 1/04 (2017.12); A61P 1/16 (2017.12); A61P 3/10 (2017.12); A61P 5/14 (2017.12); A61P 7/06 (2017.12); A61P 9/10 (2017.12); A61P 11/00 (2017.12); A61P 11/02 (2017.12); A61P 11/06 (2017.12); A61P 15/00 (2017.12); A61P 17/00 (2017.12); A61P 17/02 (2017.12); A61P 19/02 (2017.12); A61P 21/00 (2017.12); A61P 21/04 (2017.12); A61P 25/00 (2017.12); A61P 25/02 (2017.12); A61P 27/02 (2017.12); A61P 27/16 (2017.12); A61P 29/00 (2017.12); A61P 31/04 (2017.12); A61P 31/06 (2017.12); A61P 35/00 (2017.12); A61P 37/02 (2017.12); A61P 37/06 (2017.12); A61P 37/08 (2017.12); A61P 43/00 (2017.12); C12N 15/113 (2013.01); C12N 15/1138 (2013.01); C12N 15/87 (2013.01); A61K 38/00 (2013.01); C12N 2310/111 (2013.01); C12N 2310/12 (2013.01); C12N 2310/121 (2013.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2310/317 (2013.01); C12N 2310/318 (2013.01); C12N 2310/321 (2013.01); C12N 2310/322 (2013.01); C12N 2310/332 (2013.01); C12N 2310/346 (2013.01); C12N 2310/53 (2013.01)
C-Set (source: EP)
Citation (search report)
See references of WO 2005045038A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2005045038 A2 20050519; WO 2005045038 A3 20060302; WO 2005045038 A8 20050714; CA 2543029 A1 20050519; EP 1694838 A2 20060830; JP 2007527709 A 20071004
DOCDB simple family (application)
US 2004027231 W 20040820; CA 2543029 A 20040820; EP 04781836 A 20040820; JP 2006536611 A 20040820