EP 1696897 A4 20081210 - COMPOSITIONS AND METHODS FOR TREATING DIABETES
Title (en)
COMPOSITIONS AND METHODS FOR TREATING DIABETES
Title (de)
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON DIABETES
Title (fr)
COMPOSITIONS ET PROCEDES POUR LE TRAITEMENT DU DIABETE
Publication
Application
Priority
- US 2004042884 W 20041220
- US 53111903 P 20031219
- US 59170904 P 20040727
Abstract (en)
[origin: US2005137125A1] The subject invention provides compositions and methods for treating diabetes in patients. In a preferred embodiment, the invention provides compositions and methods for treating diabetes and/or preventing or alleviating complications associated with diabetes. Specifically exemplified herein is the concurrent administration of a cysteamine compound with at least one additional therapeutic agent to prevent and/or treat diabetes as well as prevent and/or treat complications associated with diabetes. In a preferred embodiment, oral administration of cysteamine hydrochloride with Metformin to a patient diagnosed with diabetes can substantially regulate the patient's glucose metabolism and insulin sensitivity.
IPC 8 full level
A61K 31/13 (2006.01); A61K 31/155 (2006.01); A61K 31/198 (2006.01); A61K 38/28 (2006.01); A61K 45/06 (2006.01); A61P 3/10 (2006.01)
CPC (source: EP KR US)
A61K 31/13 (2013.01 - EP US); A61K 31/155 (2013.01 - EP US); A61K 31/16 (2013.01 - KR); A61K 31/198 (2013.01 - EP US); A61K 38/28 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61P 1/02 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 5/50 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 13/12 (2017.12 - EP); A61P 17/00 (2017.12 - EP); A61P 17/02 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 19/06 (2017.12 - EP); A61P 21/00 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/02 (2017.12 - EP); A61P 27/02 (2017.12 - EP); A61P 27/06 (2017.12 - EP); A61P 27/12 (2017.12 - EP); A61P 31/04 (2017.12 - EP); A61P 31/10 (2017.12 - EP); A61P 37/08 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Citation (search report)
- [PX] WO 2004041257 A2 20040521 - DSM IP ASSETS BV [NL], et al
- [Y] WO 8502340 A1 19850606 - AMMON HERMANN P T [DE]
- [A] FR 2716625 A1 19950901 - GOUCHET FRANCK ARNO [FR]
- [XY] SAKO Y ET AL: "Effect of glibenclamide on pancreatic hormone release from isolated perifused islets of normal and cysteamine-treated rats", METABOLISM, CLINICAL AND EXPERIMENTAL, W.B. SAUNDERS CO., PHILADELPHIA, PA, US, vol. 35, no. 10, 1 October 1986 (1986-10-01), pages 944 - 949, XP023030765, ISSN: 0026-0495, [retrieved on 19861001]
- [XY] DONATI,C . ET AL.: "Pantetina, diabete e aterosclerosi. Indagine clinica su 1045 pazienti", LA CLINICA TERAPEUTICA, vol. 128, no. 6, 31 March 1989 (1989-03-31), pages 411 - 422, XP009107988
- [X] OBROSOVA I G ET AL: "BIOCHEMICAL MECHANISMS OF THE HYPOLIPIDEMIC EFFECT OF PANTETHINE IN INSULIN-INDEPENDENT DIABETES", KHIMIKO-FARMATSEVTICHESKII ZHURNAL, MOSCOW, RU, vol. 22, no. 11, 1 January 1988 (1988-01-01), pages 1302 - 1309, XP009030749, ISSN: 0023-1134
- See references of WO 2005063226A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
US 2005137125 A1 20050623; US 7442720 B2 20081028; AR 047779 A1 20060222; AT E515261 T1 20110715; AU 2004308934 A1 20050714; AU 2004308934 B2 20100401; BR PI0417829 A 20070410; CA 2549717 A1 20050714; CA 2549717 C 20121113; CN 101897970 A 20101201; EP 1696897 A1 20060906; EP 1696897 A4 20081210; EP 1696897 B1 20110706; HK 1099507 A1 20070817; IL 176259 A0 20061005; IL 176259 A 20160229; JP 2007514771 A 20070607; JP 4845740 B2 20111228; KR 101329369 B1 20131114; KR 20070004569 A 20070109; MX PA06007100 A 20070119; MY 143799 A 20110715; RU 2006126062 A 20080127; RU 2367423 C2 20090920; SG 149814 A1 20090227; TW 200524583 A 20050801; TW I350751 B 20111021; US 2009048154 A1 20090219; US 8188151 B2 20120529; WO 2005063226 A1 20050714
DOCDB simple family (application)
US 1716404 A 20041220; AR P040104812 A 20041220; AT 04815013 T 20041220; AU 2004308934 A 20041220; BR PI0417829 A 20041220; CA 2549717 A 20041220; CN 201010223101 A 20041220; EP 04815013 A 20041220; HK 07102258 A 20070228; IL 17625906 A 20060612; JP 2006545568 A 20041220; KR 20067013737 A 20041220; MX PA06007100 A 20041220; MY PI20045235 A 20041220; RU 2006126062 A 20041220; SG 2008094658 A 20041220; TW 93139597 A 20041220; US 2004042884 W 20041220; US 25972108 A 20081028