EP 1699770 A1 20060913 - METHOD FOR THE SYNTHESIS OF EXOCYCLIC DERIVATIVES OF CYCLOALKYL-HYDRAZINES AND EXOCYCLIC DERIVATIVES OF HETEROCYCLOALKYL-HYDRAZINES
Title (en)
METHOD FOR THE SYNTHESIS OF EXOCYCLIC DERIVATIVES OF CYCLOALKYL-HYDRAZINES AND EXOCYCLIC DERIVATIVES OF HETEROCYCLOALKYL-HYDRAZINES
Title (de)
VERFAHREN ZUR SYNTHESE VON EXOCYCLISCHEN DERIVATEN VON CYCLOALKYLHYDRAZINEN UND EXOCYCLISCHEN DERIVATEN VON HETEROCYCLOALKYLHYDRAZINEN
Title (fr)
PROCEDE DE SYNTHESE DE DERIVES DE CYCLOALKYL-HYDRAZINES EXOCYCLIQUES ET DE DERIVES D'HETEROCYCLOALKYL-HYDRAZINES EXOCYCLIQUES
Publication
Application
Priority
- FR 2004003288 W 20041217
- FR 0314795 A 20031217
Abstract (en)
[origin: FR2864081A1] Synthesis of cycloalkylhydrazines and exocyclic heterocycloalkylhydrazines (A). Synthesis of cycloalkylhydrazines and exocyclic heterocycloalkylhydrazines (A) comprises: (a) reacting, in alkaline medium at 30-60[deg]C, a heterocyclic amine (B) with a monochloroamine (C); (b) separating the resulting solution into organic and aqueous phases by adding sodium hydroxide, with cooling such that the temperature does not exceed the boiling points of the compounds; and (c) optionally isolating (A) by distillation of the organic phase.
IPC 8 full level
C07D 295/30 (2006.01)
CPC (source: EP KR US)
A61K 31/445 (2013.01 - KR); C07D 295/30 (2013.01 - EP KR US)
Citation (search report)
See references of WO 2005058852A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
FR 2864081 A1 20050624; FR 2864081 B1 20060428; CA 2550080 A1 20050630; CA 2550080 C 20120731; CN 100528853 C 20090819; CN 1894228 A 20070110; EP 1699770 A1 20060913; JP 2007514723 A 20070607; JP 4926718 B2 20120509; KR 101090539 B1 20111208; KR 20070022639 A 20070227; US 2007249829 A1 20071025; US 7879999 B2 20110201; WO 2005058852 A1 20050630
DOCDB simple family (application)
FR 0314795 A 20031217; CA 2550080 A 20041217; CN 200480037639 A 20041217; EP 04816423 A 20041217; FR 2004003288 W 20041217; JP 2006544502 A 20041217; KR 20067014401 A 20060718; US 58328404 A 20041217