EP 1701707 A2 20060920 - DRUG GRANULE COATINGS THAT IMPART SMEAR RESISTANCE DURING MECHANICAL COMPRESSION
Title (en)
DRUG GRANULE COATINGS THAT IMPART SMEAR RESISTANCE DURING MECHANICAL COMPRESSION
Title (de)
ARZNEIMITTELGRANULAT-BESCHICHTUNGEN ZUR VERLEIHUNG VON SCHMIERFESTIGKEIT BEI DER MECHANISCHEN KOMPRESSION
Title (fr)
REVETEMENTS DE GRANULES DE MEDICAMENTS DONNANT UNE RESISTANCE AU POISSAGE EN COMPRESSION MECANIQUE
Publication
Application
Priority
- US 2004043931 W 20041228
- US 53347003 P 20031229
- US 53311203 P 20031229
Abstract (en)
[origin: WO2005065647A2] A drug formulation is disclosed comprising granules having a substrate and a coating, said granule substrate comprising a solubilizing surfactant or a low solubility therapeutic drug, or both, and said granule coating comprising a hydrophilic polymer. Also disclosed is a drug formulation consisting of a tablet core made by mechanical compression, wherein said tablet core comprises granules having a substrate and a coating, said granule substrate comprising a solubilizing surfactant or a low solubility therapeutic drug, or both, and said granule coating comprising a hydrophilic polymer. Also disclosed is a dosage form for oral administration of topiramate, comprising a tablet core and an osmotic delivery system. Methods for controlling topiramate release patterns by altering the composition of the topiramate dosage form are also disclosed.
IPC 8 full level
A61K 9/20 (2006.01); A61K 9/00 (2006.01); A61K 9/50 (2006.01)
CPC (source: EP)
A61K 9/0004 (2013.01); A61K 9/5026 (2013.01); A61K 9/5047 (2013.01); A61P 25/08 (2017.12)
Citation (search report)
See references of WO 2005065647A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2005065647 A2 20050721; WO 2005065647 A3 20051208; AU 2004312083 A1 20050721; CA 2551825 A1 20050721; EP 1701707 A2 20060920; JP 2007517062 A 20070628; MX PA06007511 A 20090610
DOCDB simple family (application)
US 2004043931 W 20041228; AU 2004312083 A 20041228; CA 2551825 A 20041228; EP 04815921 A 20041228; JP 2006547568 A 20041228; MX PA06007511 A 20041228