Global Patent Index - EP 1706154 A4

EP 1706154 A4 20081126 - IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS

Title (en)

IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS

Title (de)

VERBESSERTE GASTRINFREISETZENDE PEPTIDVERBINDUNGEN

Title (fr)

COMPOSES PEPTIDIQUES DE LIBERATION DE GASTRINE AMELIORES

Publication

EP 1706154 A4 20081126 (EN)

Application

EP 04777906 A 20040712

Priority

  • US 2004022115 W 20040712
  • US 0341328 W 20031224
  • US 82892504 A 20040420

Abstract (en)

[origin: WO2005067983A1] New and improved compounds for use in diagnostic imaging or therapy having the formula M-N-O-P-G, wherein M is an optical label or a metal chelator (in the form complexed with a metal radionuclide or not), N-O-P is the linker, and G is the GRP receptor targeting peptide. Methods for imaging a patient and/or providing radiotherapy or phototherapy to a patient using the compounds of the invention are also provided. Methods and kits for preparing a diagnostic imaging agent from the compound is further provided. Methods and kits for preparing a radiotherapeutic agent are further provided.

IPC 8 full level

A61K 51/00 (2006.01); A61K 51/08 (2006.01); A61M 36/14 (2006.01)

CPC (source: EP KR)

A61K 51/00 (2013.01 - KR); A61K 51/0493 (2013.01 - EP); A61K 51/088 (2013.01 - EP); A61P 35/00 (2017.12 - EP); C07K 7/086 (2013.01 - EP); C07K 14/57572 (2013.01 - EP)

Citation (search report)

  • [E] WO 2004065407 A2 20040805 - BRACCO IMAGING SPA [IT], et al
  • [X] WO 02087631 A1 20021107 - UNIV MISSOURI SYSTEM [US], et al
  • [A] US 2003171561 A1 20030911 - PILLAI RADHAKRISHNA K [US], et al
  • [A] US 5474756 A 19951212 - TWEEDLE MICHAEL F [US], et al
  • [A] WO 9532741 A1 19951207 - BRACCO SPA [IT], et al
  • [A] WO 0038738 A1 20000706 - BRACCO INT BV [NL], et al
  • [E] WO 2004062574 A2 20040729 - BRACCO IMAGING SPA [IT], et al
  • [A] WO 0162777 A1 20010830 - DABUR RES FOUNDATION [IN], et al
  • [A] US 2003050436 A1 20030313 - COY DAVID H [US], et al
  • [A] US 5723578 A 19980303 - COY DAVID H [US], et al
  • [X] SMITH C J ET AL: "Gastrin releasing peptide (GRP) receptor targeted radiopharmaceuticals: A concise update", NUCLEAR MEDICINE AND BIOLOGY, ELSEVIER, NY, US, vol. 30, no. 8, 1 November 2003 (2003-11-01), pages 861 - 868, XP004482850, ISSN: 0969-8051
  • [X] HOFFMAN T J ET AL: "NOVEL SERIES OF 111IN-LABELED BOMBESIN ANALOGS AS POTENTIAL RADIOPHARMACEUTICALS FOR SPECIFIC TARGETING OF GASTRIN-RELEASING PEPTIDE RECEPTORS EXPRESSED ON HUMAN PROSTATE CANCER CELLS", JOURNAL OF NUCLEAR MEDICINE, SOCIETY OF NUCLEAR MEDICINE, RESTON, VA, US, vol. 44, no. 5, 1 January 2003 (2003-01-01), pages 823 - 831, XP008051690, ISSN: 0161-5505
  • [X] SMITH C J ET AL: "Radiochemical investigations of <177>Lu-DOTA-8-Aoc-BBN[7-14]NH2: an in vitro/in vivo assessment of the targeting ability of this new radiopharmaceutical for PC-3 human prostate cancer cells", NUCLEAR MEDICINE AND BIOLOGY, ELSEVIER, NY, US, vol. 30, no. 2, 1 February 2003 (2003-02-01), pages 101 - 109, XP004413110, ISSN: 0969-8051
  • [PX] ROGERS B E ET AL: "IN VITRO AND IN VIVO EVALUATION OF A 64C-LABELED POLYETHYLENE GLYCOL-BOMBESIN CONJUGATE", CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, LIEBERT, US, vol. 19, no. 1, 1 January 2004 (2004-01-01), pages 25 - 34, XP008051692
  • See references of WO 2005067983A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2005067983 A1 20050728; AU 2004314112 A1 20050728; BR PI0418194 A 20070427; CA 2549318 A1 20050728; EP 1706154 A1 20061004; EP 1706154 A4 20081126; IL 175785 A0 20061005; JP 2008501627 A 20080124; KR 20060121244 A 20061128; RU 2006126637 A 20080127

DOCDB simple family (application)

US 2004022115 W 20040712; AU 2004314112 A 20040712; BR PI0418194 A 20040712; CA 2549318 A 20040712; EP 04777906 A 20040712; IL 17578506 A 20060521; JP 2006546954 A 20040712; KR 20067012647 A 20060623; RU 2006126637 A 20040712