Global Patent Index - EP 1709995 A1

EP 1709995 A1 20061011 - Asthma/allergy therapy using nigella sativa

Title (en)

Asthma/allergy therapy using nigella sativa

Title (de)

Asthma- und Allergiebehandlung unter Verwendung von Nigella Sativa

Title (fr)

Traitement de l'asthme et de l'allergie utilisant nigella sativa

Publication

EP 1709995 A1 20061011 (EN)

Application

EP 06114106 A 20000302

Priority

  • EP 00909548 A 20000302
  • GB 9904777 A 19990302
  • GB 9913341 A 19990608

Abstract (en)

Pure seeds of Nigella sativa or Nigella sativa extract are used in the manufacture of a medicament for the treatment and/or prophylaxis of asthma/allegy in a mammal such as a human, wherein the medicament is presented in a form for short term therapy by administration over a period 1 to 30 days, preferably over 3 to 5 days, to produce a long term clinical remission of the type I hypersensitivity reaction/allergy over a period of months.

IPC 8 full level

A61P 11/00 (2006.01); A61K 36/00 (2006.01); A61K 36/71 (2006.01); A61K 38/17 (2006.01); A61P 37/00 (2006.01); A61P 37/04 (2006.01)

CPC (source: EP US)

A61K 36/71 (2013.01 - EP US); A61P 11/00 (2017.12 - EP); A61P 11/06 (2017.12 - EP); A61P 37/00 (2017.12 - EP); A61P 37/04 (2017.12 - EP); A61P 37/06 (2017.12 - EP); A61P 37/08 (2017.12 - EP)

Citation (applicant)

  • JP H01224320 A 19890907 - SHIMIZU KAGAKU KK
  • JP S6348345 A 19880301 - IDEMITSU PETROCHEMICAL CO
  • WO 9505839 A1 19950302 - MEDENICA RAJKO D [US]
  • US 5648089 A 19970715 - SHAWKAT TAREK [US]
  • BARNES P J, THE NEW ENGLAND JOURNAL OF MEDICINE, vol. 341, no. 26, 23 December 1999 (1999-12-23)
  • VILLARUBIA, V.G. ET AL., IMMUNOTOXICOL, vol. 19, no. 1, 1997, pages 53 - 74
  • MOYA P; BAIXERAS E; BARASOAIN I.: "Inmunoferon enhances the activities of early-type interferon inducers and natural killer cells", IMMUNOPHARMACOL. IMMUNOTOXICOL., vol. 9, no. 2-3, 1987, pages 234 - 56
  • PAULESU L; BOCCI V; PESSINA G P ET AL.: "Interferon induction in rabbits after intraduodenal administration of a phosphorylated glycomannan-protein fraction of the cell wall of Candida albicans", IMMUNOL. LETT., vol. 27, no. 3, 1991, pages 231 - 5
  • SAYED M D.: "Traditional medicine in health care.", J ETHNOPHARMACOL, vol. 2, no. 1, March 1980 (1980-03-01), pages 19 - 22
  • MAHFOUZ M; EL - DAKHAKHNY M: "chemical and pharmacological properties of the new anti - asthmatic drug, nigellone", EGYPT PHARRN BUL, vol. 42, 1960, pages 411 - 424
  • EL - TAHIR KEH; ASHOUR MMS: "The respiratory effect of the volatile oil of the black seed ( Nigella sativa ) in guinea - pig : elucidation of the michanism (s) of action", GEN PHARMACOL, vol. 24, 1993, pages 1115 - 1122

Citation (search report)

  • [X] MERFORT I ET AL: "Flavonol triglycosides from seeds of Nigella sativa", PHYTOCHEMISTRY, PERGAMON PRESS, GB, vol. 46, no. 2, September 1997 (1997-09-01), pages 359 - 363, XP004293450, ISSN: 0031-9422
  • [DA] REITER M ET AL: "RELAXANT EFFECTS ON TRACHEAL AND ILEAL SMOOTH MUSCLES OF THE GUINEA PIG", ARZNEIMITTEL FORSCHUNG. DRUG RESEARCH, ECV EDITIO CANTOR VERLAG, AULENDORF, DE, vol. 35, no. 1, 1985, pages 408 - 414, XP002950767, ISSN: 0004-4172
  • [DA] MUTABAGANI A ET AL: "A STUDY OF THE ANTI-INFLAMMATORY ACTIVITY OF NIGELLA SATIVE L. AND THYMOQUINONE IN RATS", SAUDI PHARMACEUTICAL JOURNAL, SAUDI PHARMACEUTICAL SOCIETY, RIYAD, SA, vol. 5, no. 2/3, 1997, pages 110 - 113, XP000964634, ISSN: 1319-0164
  • [DX] EL TAHIR K E ET AL: "The respiratory effects of the volatile oil of the black seed (Nigella sativa) in guinea-pigs: elucidation of the mechanism(s) of action.", GENERAL PHARMACOLOGY. SEP 1993, vol. 24, no. 5, September 1993 (1993-09-01), pages 1115 - 1122, XP002395704, ISSN: 0306-3623
  • [DX] SAYED M D: "Traditional medicine in health care.", JOURNAL OF ETHNOPHARMACOLOGY. MAR 1980, vol. 2, no. 1, March 1980 (1980-03-01), pages 19 - 22, XP002395705, ISSN: 0378-8741
  • [DX] ELKADI A ET AL: "NIGELLA SATIVA AND CELL-MEDIATED IMMUNITY", ARCHIVES OF AIDS RESEARCH, REPRODUCTIVE HEALTH CENTER, KIAWAH ISLAND, SC, US, vol. 1, no. 2/3, 1987, pages 232 - 233, XP000964740, ISSN: 0899-4811
  • [T] BUYUKOZTURK ET AL: "Nigella sativa (black seed) oil does not affect the T-helper 1 and T-helper 2 type cytokine production from splenic mononuclear cells in allergen sensitized mice", JOURNAL OF ETHNOPHARMACOLOGY, ELSEVIER SCIENTIFIC PUBLISHERS LTD, IE, vol. 100, no. 3, 14 September 2005 (2005-09-14), pages 295 - 298, XP005041903, ISSN: 0378-8741
  • [DX] BOSKABADY M H ET AL: "Bronchodilatory and anticholinergic effects of nigella sativa on isolated guinea-pig tracheal chain", EUROPEAN RESPIRATORY JOURNAL SUPPLEMENT, vol. 10, no. 25, September 1997 (1997-09-01), & ANNUAL CONGRESS OF THE EUROPEAN RESPIRATORY SOCIETY; BERLIN, GERMANY; SEPTEMBER 20-24, 1997, pages 53S, XP009071364, ISSN: 0904-1850

Citation (third parties)

Third party :

  • AGNIVESA: "Ksavathuharatvajadiyogah", KEY ATTRIBUTES OF TKDL BP/2381E, vol. 5, 2000, pages 1 - 2, XP003024897
  • MOHD. AKBAR ARZANI: "Zaroor Abyaz Ba Nuskha Deegar", KEY ATTRIBUTES OF TKDL MH5/454, pages 1 - 3, XP003024898
  • ABU ALI IBN SINA: "Al Qanoon fil Tibb", KEY ATTRIBUTES OF TKDL AH2/419, vol. 5, pages 1 - 3, XP003024899
  • KANDASAMY MUDALIAR: "Irumanjal Ennai", KEY ATTRIBUTES OF TKDL AM05/239, 1879, pages 1 - 3, XP003024900
  • AGASTHIYAR: "Vanasappathira Ennai", KEY ATTRIBUTES OF TKDL AM04/261, 1933, pages 1 - 3, XP003025001

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

US 2002061841 A1 20020523; US 7592327 B2 20090922; EP 1709995 A1 20061011; GB 0003115 D0 20000405; GB 9904777 D0 19990428; HK 1049964 A1 20030606; US 2010040714 A1 20100218

DOCDB simple family (application)

US 94456401 A 20010904; EP 06114106 A 20000302; GB 0003115 A 20000208; GB 9904777 A 19990302; HK 03102127 A 20030324; US 53973109 A 20090812