EP 1711497 A1 20061018 - 2-(3-SUBSTITUTED-ARYL)AMINO-4-ARYL-THIAZOLES AS TYROSINE KINASE INHIBITORS
Title (en)
2-(3-SUBSTITUTED-ARYL)AMINO-4-ARYL-THIAZOLES AS TYROSINE KINASE INHIBITORS
Title (de)
2-(3-SUBSTITUIERTES ARYL)AMINO-4-ARYL-THIAZOLE ALS TYROSINKINASEINHIBITOREN
Title (fr)
2-(3-SUBSTITUES ARYLE)AMINO-4-ARYLE-THIAZOLES EN TANT QU'INHIBITEURS DE TYROSINE KINASE
Publication
Application
Priority
- IB 2005000401 W 20050128
- US 54006404 P 20040130
Abstract (en)
[origin: WO2005073225A1] The present invention relates to novel compounds selected from 2-(3substitutedaryl)amino-4-aryl-thiazoles that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective c-kit inhibitors.
IPC 8 full level
A61K 31/4439 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01)
CPC (source: EP KR)
A61P 1/04 (2017.12 - EP); A61P 3/00 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 11/00 (2017.12 - EP); A61P 13/10 (2017.12 - EP); A61P 19/00 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 31/04 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 35/02 (2017.12 - EP); A61P 37/06 (2017.12 - EP); A61P 37/08 (2017.12 - EP); C07D 417/04 (2013.01 - EP KR); C07D 417/14 (2013.01 - EP KR)
Citation (search report)
See references of WO 2005073225A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR LV MK YU
DOCDB simple family (publication)
WO 2005073225 A1 20050811; AU 2005209485 A1 20050811; BR PI0507271 A 20070626; CA 2554925 A1 20050811; CN 1934107 A 20070321; EP 1711497 A1 20061018; IL 177007 A0 20061210; JP 2007519711 A 20070719; KR 20060129413 A 20061215; NO 20063861 L 20061023; NZ 548884 A 20100625; ZA 200606152 B 20071128
DOCDB simple family (application)
IB 2005000401 W 20050128; AU 2005209485 A 20050128; BR PI0507271 A 20050128; CA 2554925 A 20050128; CN 200580008189 A 20050128; EP 05702517 A 20050128; IL 17700706 A 20060720; JP 2006550363 A 20050128; KR 20067017411 A 20060829; NO 20063861 A 20060830; NZ 54888405 A 20050128; ZA 200606152 A 20060725