Global Patent Index - EP 1712634 A1

EP 1712634 A1 20061018 - Selection of highly efficient antigen presenting cells for regulating immunity and uses thereof

Title (en)

Selection of highly efficient antigen presenting cells for regulating immunity and uses thereof

Title (de)

Verfahren zur Auswahl von effizienten antigen präsentierenden Zellen und ihre Anwendung in der Regulation der Immunität

Title (fr)

Procédé pour la sélection des cellules présentatrices d'antigène efficaces et leur utilisation pour la régulation de l'immunité

Publication

EP 1712634 A1 20061018 (EN)

Application

EP 05290815 A 20050413

Priority

EP 05290815 A 20050413

Abstract (en)

The present invention relates, generally, to the fields of immunology and cellular biology. The invention discloses, more particularly, a new strategy of modulation of immune response based on the use of highly efficient non autologous antigen presenting and/or immunostimulatory system such as allogeneic antigen presenting cells. Invention thus relates to methods for preparing or selecting systems having high antigen presentation and/or immunostimulatory capacity for a given subject. The invention also discloses banks usable to select such systems as well as compositions comprising such systems, their preparation and uses.

IPC 8 full level

C12Q 1/00 (2006.01); A61K 45/00 (2006.01); G01N 33/50 (2006.01)

CPC (source: EP)

A61K 39/4615 (2023.05); A61K 39/4622 (2023.05); A61K 39/464491 (2023.05); A61K 39/464838 (2023.05); A61K 45/06 (2013.01); G01N 33/5005 (2013.01); G01N 33/5047 (2013.01)

Citation (search report)

  • [X] WO 9947687 A1 19990923 - GENZYME CORP [US], et al
  • [X] WO 02074338 A1 20020926 - GSF FORSCHUNGSGESELLSCHAFT FUE [DE], et al
  • [X] WO 2004002415 A2 20040108 - DANA FARBER CANCER INST INC [US], et al
  • [X] WO 03103707 A1 20031218 - IMMUNICUM AB [SE], et al
  • [A] US 5728378 A 19980317 - HELLSTRAND KRISTOFFER [SE], et al
  • [A] US 5962320 A 19991005 - ROBINSON WILLIAM S [US]
  • [X] PESHWA MADHUSUDAN V ET AL: "Generation of primary peptide-specific CD8+ cytotoxic T-lymphocytes in vitro using allogeneic dendritic cells", CELL TRANSPLANTATION, ELSEVIER SCIENCE, US, vol. 7, no. 1, January 1998 (1998-01-01), pages 1 - 9, XP002195712, ISSN: 0963-6897
  • [A] SIMOVA J ET AL: "Immunotherapeutic efficacy of vaccines generated by fusion of dendritic cells and HPV16-associated tumour cells", FOLIA BIOLOGICA (PRAGUE), vol. 51, no. 1, 2005, pages 19 - 24, XP009053964, ISSN: 0015-5500
  • [A] HUS IWONA ET AL: "The first experience with allogeneic dendritic cells vaccines in ZAP-70 positive and negative untreated B-CLL in early stages of disease.", BLOOD, vol. 102, no. 11, 16 November 2003 (2003-11-16), & 45TH ANNUAL MEETING OF THE AMERICAN SOCIETY OF HEMATOLOGY; SAN DIEGO, CA, USA; DECEMBER 06-09, 2003, pages 435a, XP009054045, ISSN: 0006-4971

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR LV MK YU

DOCDB simple family (publication)

EP 1712634 A1 20061018; AU 2006233355 A1 20061019; CA 2604187 A1 20061019; EP 1882041 A2 20080130; WO 2006109193 A2 20061019; WO 2006109193 A3 20061130

DOCDB simple family (application)

EP 05290815 A 20050413; AU 2006233355 A 20060412; CA 2604187 A 20060412; EP 06744824 A 20060412; IB 2006001523 W 20060412