Global Patent Index - EP 1713455 A2

EP 1713455 A2 20061025 - METHOD FOR PRODUCING SORBICILLACTONE A

Title (en)

METHOD FOR PRODUCING SORBICILLACTONE A

Title (de)

VERFAHREN ZUR HERSTELLUNG VON SORBICILLACTON A

Title (fr)

PROCEDE POUR PRODUIRE DU SORBICILLACTONE A

Publication

EP 1713455 A2 20061025 (DE)

Application

EP 05701272 A 20050131

Priority

  • EP 2005000923 W 20050131
  • DE 102004004901 A 20040130

Abstract (en)

[origin: WO2005072711A2] The invention relates to an improved method for cultivating the fungus Penicillium chrysogenum, especially strain KIP 3201, for producing the antitumoral natural substance Sorbicillactone A of formula (I) and its derivatives in an optimized manner and in large amounts. The invention also relates to an optimized method for obtaining and purifying said substance from the fungal biomass and from the culture medium. The invention also describes the biological activity of Sorbicillactone A of formula (I) and investigations relating to the genotoxicity of the compound.

IPC 8 full level

A61K 31/00 (2006.01); A61K 31/343 (2006.01); C07D 307/83 (2006.01); C12N 1/38 (2006.01); C12P 17/04 (2006.01)

CPC (source: EP US)

A61K 31/343 (2013.01 - EP US); A61P 25/00 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 31/00 (2017.12 - EP); A61P 31/04 (2017.12 - EP); A61P 31/10 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 35/02 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 307/83 (2013.01 - EP US); C12P 17/04 (2013.01 - EP US)

Citation (search report)

See references of WO 2005072711A2

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2005072711 A2 20050811; WO 2005072711 A3 20050915; CA 2554733 A1 20050811; DE 102004004901 A1 20050825; DE 102004004901 B4 20060105; EP 1713455 A2 20061025; JP 2007519414 A 20070719; US 2007135515 A1 20070614

DOCDB simple family (application)

EP 2005000923 W 20050131; CA 2554733 A 20050131; DE 102004004901 A 20040130; EP 05701272 A 20050131; JP 2006550128 A 20050131; US 58809905 A 20050131