Global Patent Index - EP 1715857 A1

EP 1715857 A1 20061102 - AMIDINE DERIVATIVES FOR TREATING AMYLOIDOSIS

Title (en)

AMIDINE DERIVATIVES FOR TREATING AMYLOIDOSIS

Title (de)

AMIDINE ZUR BEHANDLUNG VON AMYLOIDOSE

Title (fr)

DERIVES D'AMIDINE POUR LE TRAITEMENT DE L'AMYLOSE

Publication

EP 1715857 A1 20061102 (EN)

Application

EP 04704686 A 20040123

Priority

IB 2004000617 W 20040123

Abstract (en)

[origin: WO2005079780A1] The present invention relates to the use of amidine compounds in the treatment of amyloid-related diseases. In particular, the invention relates to a method of treating or preventing an amyloid-related disease in a subject comprising administering to the subject a therapeutic amount of an amidine compound. Among the compounds for use according to the invention are those according to the following Formula (I), such that, when administered, amyloid fibril formation, neurodegeneration, or cellular toxicity is reduced or inhibited: Formula (I).

IPC 8 full level

A61K 31/155 (2006.01); A61K 31/167 (2006.01); A61K 31/18 (2006.01); A61K 31/4168 (2006.01); A61P 3/10 (2006.01); A61P 5/50 (2006.01); A61P 25/28 (2006.01); A61P 43/00 (2006.01)

CPC (source: EP)

A61K 31/155 (2013.01); A61K 31/167 (2013.01); A61K 31/18 (2013.01); A61K 31/4168 (2013.01); A61P 3/10 (2017.12); A61P 5/50 (2017.12); A61P 25/28 (2017.12); A61P 27/02 (2017.12); A61P 43/00 (2017.12)

Citation (search report)

See references of WO 2005079780A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

Designated extension state (EPC)

AL LT LV MK

DOCDB simple family (publication)

WO 2005079780 A1 20050901; AU 2004316081 A1 20050901; CA 2552094 A1 20050901; EP 1715857 A1 20061102; JP 2007518786 A 20070712

DOCDB simple family (application)

IB 2004000617 W 20040123; AU 2004316081 A 20040123; CA 2552094 A 20040123; EP 04704686 A 20040123; JP 2006550316 A 20040123