EP 1716166 A2 20061102 - 17-METHYLENE- OR 17-SPIRO-CYCLOPROPANE 7-SUBSTITUTED ESTRA-1,3,5(10)-TRIENE DERIVATIVES WITH ANTI-ESTROGENIC ACTIVITY
Title (en)
17-METHYLENE- OR 17-SPIRO-CYCLOPROPANE 7-SUBSTITUTED ESTRA-1,3,5(10)-TRIENE DERIVATIVES WITH ANTI-ESTROGENIC ACTIVITY
Title (de)
17-METHYLEN- ODER 17-SPIRO-CYCLOPROPAN 7-SUBSTITUIERTE ESTRA-1,3,5(10)-TRIEN DERIVATE MIT ANTI-ESTROGENISCHER AKTIVITÄT
Title (fr)
DERIVES D' ESTRA-1,3,5(10)-TRIENE SUBSTITUES PAR UN RESTE 17-METHYLENE OU 17-SPIROCYCLOPROPANE A ACTIVITE ANTI-ESTROGENE
Publication
Application
Priority
- SE 2005000188 W 20050211
- SE 0400346 A 20040213
- US 54392204 P 20040213
Abstract (en)
[origin: WO2005077968A2] The present invention relates to novel compounds which are 7alpha-substituted 17-alkylene-16alpha-hydroxy steroidal estrogens. This invention specifically relates to estrogen derivatives which contain 7alpha-substituents and which exhibit anti-estrogenic properties. The present invention also relates to use of said compounds as a medicament, and for the treatment of estrogen dependent disorders, a pharmaceutical composition comprising one or more of said compounds and a method of treatment.
IPC 8 full level
C07J 13/00 (2006.01); A61K 31/56 (2006.01); A61K 31/57 (2006.01); A61P 5/32 (2006.01); C07J 3/00 (2006.01); C07J 31/00 (2006.01); C07J 41/00 (2006.01); C07J 53/00 (2006.01)
IPC 8 main group level
C07D (2006.01)
CPC (source: EP US)
A61P 5/32 (2017.12 - EP); A61P 35/00 (2017.12 - EP); C07J 3/00 (2013.01 - EP US); C07J 53/00 (2013.01 - EP US)
Citation (search report)
See references of WO 2005077968A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR LV MK YU
DOCDB simple family (publication)
WO 2005077968 A2 20050825; WO 2005077968 A3 20060831; WO 2005077968 A8 20061116; WO 2005077968 B1 20070104; AU 2005212210 A1 20050825; CA 2552843 A1 20050825; CN 101076538 A 20071121; EP 1716166 A2 20061102; JP 2007522211 A 20070809; SE 0400346 D0 20040213; SE 0400346 L 20050814; SE 527131 C2 20051227; US 2007142345 A1 20070621
DOCDB simple family (application)
SE 2005000188 W 20050211; AU 2005212210 A 20050211; CA 2552843 A 20050211; CN 200580004725 A 20050211; EP 05711049 A 20050211; JP 2006553092 A 20050211; SE 0400346 A 20040213; US 58756105 A 20050211