EP 1722792 A1 20061122 - SELECTED CGRP-ANTAGONISTS, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS
Title (en)
SELECTED CGRP-ANTAGONISTS, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS
Title (de)
AUSGEWÄHLTE CGRP-ANTAGONISTEN, VERFAHREN ZU DEREN HERSTELLUNG SOWIE DEREN VERWENDUNG ALS ARZNEIMITTEL
Title (fr)
ANTAGONISTES DE CGRP SELECTIONNES, PROCEDES DE FABRICATION ET UTILISATION EN TANT QUE MEDICAMENT
Publication
Application
Priority
- EP 2005002082 W 20050226
- DE 102004010254 A 20040303
- DE 102004028751 A 20040615
Abstract (en)
[origin: WO2005084672A1] The invention relates to substituted piperidines of general formula (I), wherein A, B, D, E, X, R<1> and R<2> have the meaning cited in claim 1, and to the tautomers, diastereomers, enantiomers, hydrates, mixtures and salts thereof, in addition to the hydrate of the salts, in particular the physiologically compatible salts thereof having inorganic or organic acids. The invention also relates to medicaments containing said compounds, to the use thereof and method for the production thereof.
IPC 8 full level
A61K 31/435 (2006.01); A61K 31/445 (2006.01); A61K 31/4545 (2006.01); A61K 31/54 (2006.01); A61K 31/55 (2006.01); A61P 5/00 (2006.01); C07D 401/14 (2006.01)
CPC (source: EP US)
A61P 5/00 (2017.12 - EP); A61P 25/06 (2017.12 - EP); C07D 401/14 (2013.01 - EP US)
Citation (search report)
See references of WO 2005084672A1
Citation (examination)
BURGEY C.S. ET AL: "Benzodiazepine calcitonin gene-related peptide (CGRP) receptor antagonists: Opimization of the 4-substituted piperidine", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 16, 2006, pages 5052 - 5056
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
BA HR YU
DOCDB simple family (publication)
WO 2005084672 A1 20050915; EP 1722792 A1 20061122; US 2005227968 A1 20051013; US 7205294 B2 20070417
DOCDB simple family (application)
EP 2005002082 W 20050226; EP 05715592 A 20050226; US 7334105 A 20050303