EP 1727536 A1 20061206 - BETA-LAPACHONE AND S-PHASE DRUG COMBINATIONS FOR CANCER TREATMENT
Title (en)
BETA-LAPACHONE AND S-PHASE DRUG COMBINATIONS FOR CANCER TREATMENT
Title (de)
BETA-LAPACHON UND S-PHASEN-ARZNEIMITTELKOMBINATIONEN FÜR DIE KREBSBEHANDLUNG
Title (fr)
COMBINAISONS DE BETA-LAPACHONE ET DE MEDICAMENT EN PHASE S POUR LE TRAITEMENT DU CANCER
Publication
Application
Priority
- US 2005005620 W 20050223
- US 54728704 P 20040223
- US 6845905 A 20050218
- US 6074705 A 20050218
Abstract (en)
[origin: WO2005082354A1] Cancers and /or malignancies can be treated by administration of a G1/S phase drug, which is preferably beta-lapachone, or a pharmaceutically acceptable salt, prodrug, metabolite, analog or derivative thereof, combined with an S phase drug, which is advantageously gemcitabine. This combination of a G1/S phase drug with an S phase drug results in an unexpectedly effective treatment of cancer. The invention includes methods of treating cancers by administering a combination of a G1/S phase drug and an S phase drug, pharmaceutical compositions comprising the combination of drugs used in these methods, as well as pharmaceutical kits.
IPC 8 full level
A61K 31/352 (2006.01); A61K 31/7064 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP)
A61K 31/352 (2013.01); A61K 31/7064 (2013.01); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 43/00 (2017.12)
Citation (search report)
See references of WO 2005082354A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2005082354 A1 20050909; CA 2556759 A1 20050909; EP 1727536 A1 20061206; JP 2007523215 A 20070816
DOCDB simple family (application)
US 2005005620 W 20050223; CA 2556759 A 20050223; EP 05713938 A 20050223; JP 2007500925 A 20050223