EP 1732546 A2 20061220 - NOVEL PYRROLO (2,3-B)PYRIDINE DERIVATIVES, THE PREPARATION AND THE PHARMACEUTICAL USE THEREOF IN THE FORM OF KINASE INHIBITORS
Title (en)
NOVEL PYRROLO (2,3-B)PYRIDINE DERIVATIVES, THE PREPARATION AND THE PHARMACEUTICAL USE THEREOF IN THE FORM OF KINASE INHIBITORS
Title (de)
NEUE PYRROLO (2,3-B)PYRIDIN-DERIVATE, IHRE HERSTELLUNG UND PHARMAZEUTISCHE VERWENDUNG IN FORM VON KINASE-HEMMERN
Title (fr)
NOUVEAUX DERIVES PYRROLO(2,3-B)PYRIDINE, LEUR PREPARATION ET LEUR UTILISATION PHARMACEUTIQUE COMME INHIBITEURS DE KINASES
Publication
Application
Priority
- FR 2005000773 W 20050330
- FR 0403354 A 20040331
Abstract (en)
[origin: WO2005095399A2] The invention relates to novel products of formula (I), wherein R is hydrogen or selected from R2 or R3, R1 is alkenyl or alkyl possibly substituted by CO-NR7R8, -NR7R8, carboxy, hydroxyl, alkoxy or halogen, identical or different R2 and R3 are alkyl or -O-alkyl or possibly substituted by -CO-NR7R8, -NR7R8, alkoxy, alkoxy-NR7R8, carboxy or phenyl, identical or different R4, R5 and R6 are hydrogen, halogen, cyano, amino, alkoxy or alkyl, R4 is also -CH=O, -CH=N-OH and -CH2NHOH, R7 and R8 are, in particular hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkenyl, heterocycloalkyl, aryl and heteroaryl or R7 and R8 form with an nitrogen atom a possibly substituted heterocycle, said products are embodied in the form of all types of isomers and salts used as drugs.
IPC 8 full level
A61K 31/437 (2006.01); A61P 35/00 (2006.01); C07D 471/04 (2006.01)
CPC (source: EP KR US)
A61K 31/4353 (2013.01 - KR); A61K 31/437 (2013.01 - KR); A61P 3/00 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 7/02 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 9/14 (2017.12 - EP); A61P 11/06 (2017.12 - EP); A61P 13/12 (2017.12 - EP); A61P 17/06 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 21/00 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 27/02 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 35/02 (2017.12 - EP); A61P 37/08 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 471/04 (2013.01 - EP KR US)
Citation (search report)
See references of WO 2005095399A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR LV MK YU
DOCDB simple family (publication)
WO 2005095399 A2 20051013; WO 2005095399 A3 20060601; AR 048344 A1 20060419; AU 2005229452 A1 20051013; BR PI0509564 A 20070925; CA 2558923 A1 20051013; CN 1950083 A 20070418; EP 1732546 A2 20061220; FR 2868422 A1 20051007; FR 2868422 B1 20060714; IL 178310 A0 20070211; JP 2007530645 A 20071101; JP 4841543 B2 20111221; KR 20070014151 A 20070131; MX PA06011161 A 20071210; TW 200602344 A 20060116; US 2007093480 A1 20070426; US 2009233956 A1 20090917; US 7528147 B2 20090505; US 7968566 B2 20110628; UY 28835 A1 20051031
DOCDB simple family (application)
FR 2005000773 W 20050330; AR P050101222 A 20050330; AU 2005229452 A 20050330; BR PI0509564 A 20050330; CA 2558923 A 20050330; CN 200580013791 A 20050330; EP 05746934 A 20050330; FR 0403354 A 20040331; IL 17831006 A 20060926; JP 2007505596 A 20050330; KR 20067021575 A 20061018; MX PA06011161 A 20050330; TW 94109913 A 20050330; US 41013509 A 20090324; US 54105106 A 20060929; UY 28835 A 20050331