EP 1732942 A2 20061220 - SYNTHETIC CHEMOKINES, METHODS OF MANUFACTURE, AND USES
Title (en)
SYNTHETIC CHEMOKINES, METHODS OF MANUFACTURE, AND USES
Title (de)
SYNTHETISCHE CHEMOKINE, HERSTELLUNGSVERFAHREN UND ANWENDUNGEN
Title (fr)
CHIMIOKINES DE SYNTHESE, LEURS PROCEDES DE PRODUCTION, ET LEURS UTILISATIONS
Publication
Application
Priority
- US 2005010212 W 20050325
- US 55740004 P 20040330
Abstract (en)
[origin: WO2005097168A2] The invention relates to synthetic chemokines, methods of manufacture and uses thereof. The synthetic chemokines of the invention include one or more amino acid deletions at the C-terminus relative to the corresponding wild type chemokine, which also can include one or more covalently attached polymers, as well one or more additional amino acid changes or chemical modifications. The invention also provides synthetic chemokines in a substantially purified oligomeric form, such as, in a monomer or dimer form. Further provided are methods for synthesizing the synthetic chemokines of the invention, pharmaceutical formulations and kits thereof, and their use as research tools and medicaments.
IPC 8 full level
A61K 38/19 (2006.01); C07K 1/00 (2006.01); C07K 14/52 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
C07K 14/521 (2013.01); A61K 38/00 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR LV MK YU
DOCDB simple family (publication)
WO 2005097168 A2 20051020; WO 2005097168 A3 20061005; AU 2005231338 A1 20051020; CA 2561171 A1 20051020; CN 101006096 A 20070725; EP 1732942 A2 20061220; EP 1732942 A4 20081203; ZA 200608279 B 20071227
DOCDB simple family (application)
US 2005010212 W 20050325; AU 2005231338 A 20050325; CA 2561171 A 20050325; CN 200580017230 A 20050325; EP 05732998 A 20050325; ZA 200608279 A 20070921