EP 1737887 A2 20070103 - BOB-1 SPECIFIC T CELLS AND METHODS TO USE
Title (en)
BOB-1 SPECIFIC T CELLS AND METHODS TO USE
Title (de)
BOB-1 SPEZIFISCHE T-ZELLEN UND DEREN VERWENDUNGEN
Title (fr)
LYMPHOCYTES SPÉCIFIQUES À L' ANTIGÈNE BOB-1 ET LEURS UTILISATIONS
Publication
Application
Priority
- EP 2005003947 W 20050414
- EP 04008880 A 20040414
- EP 05729963 A 20050414
Abstract (en)
[origin: EP1589030A1] The present invention refers to the use of Bob-1 protein, fragments or epitopes thereof and/or related sequences in a method to identify, to induce and/or to isolate Bob-1 specific or Bob-1 cross-reactive T-cells, preferably cytotoxic T-lymphocytes (CTL) and CD4<+> T-helper cells. The T-cells according to the invention can be used to identify and diagnose various diseases, which are influenced by Bob-1 protein expression. The invention provides further the use of Bob-1 specific and/or Bob-1 cross-reactive T-cells, as well as peptides and/or nucleic acid sequences for inducing Bob-1 specific and/or Bob-1 cross-reactive T-cells, as medicament or vaccine and for the treatment of Bob-1 expressing tumors, lymphomas and autoimmune diseases. <IMAGE>
IPC 8 full level
C07K 14/47 (2006.01); C12N 5/06 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP US)
A61K 39/46 (2023.05 - EP); A61K 39/4611 (2023.05 - EP); A61K 39/4621 (2023.05 - EP); A61K 39/46433 (2023.05 - EP); A61K 39/464838 (2023.05 - EP); A61P 31/18 (2018.01 - EP); A61P 35/02 (2018.01 - EP); A61P 37/00 (2018.01 - EP); A61P 37/02 (2018.01 - EP); A61P 37/08 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07K 14/47 (2013.01 - EP US); A61K 39/00 (2013.01 - US); A61K 2239/48 (2023.05 - EP)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
EP 1589030 A1 20051026; AU 2005233289 A1 20051027; CA 2562892 A1 20051027; EP 1737887 A2 20070103; JP 2008509878 A 20080403; US 2007161108 A1 20070712; WO 2005100390 A2 20051027; WO 2005100390 A3 20060427
DOCDB simple family (application)
EP 04008880 A 20040414; AU 2005233289 A 20050414; CA 2562892 A 20050414; EP 05729963 A 20050414; EP 2005003947 W 20050414; JP 2007507757 A 20050414; US 58213606 A 20061016