EP 1738167 A4 20080319 - METHOD OF DIAGNOSING THE CHANCES OF PREGNANCY AND THE DIAGNOSTIC KIT FOR THE SAME
Title (en)
METHOD OF DIAGNOSING THE CHANCES OF PREGNANCY AND THE DIAGNOSTIC KIT FOR THE SAME
Title (de)
VERFAHREN ZUR DIAGNOSE DER CHANCEN EINER SCHWANGERSCHAFT SOWIE DIAGNOSTISCHER KIT DAFÜR
Title (fr)
PROCEDE DE DIAGNOSTIC DES PROBABILITES DE GROSSESSE ET TROUSSE DE DIAGNOSTIC ASSOCIEE
Publication
Application
Priority
KR 2004000688 W 20040326
Abstract (en)
[origin: WO2005093408A1] Disclosed is a method of diagnosing the chances of pregnancy and the diagnostic kit for the method. In the present invention, follicular fluid is retrieved from the women who attended the in vitro fertilization program and MMP activity is measured. According to the present invention, the chance of pregnancy in the group with low MMP-9 activity is zero whereas in the group with high MMP-9 activity, the chances are 50-60%. Therefore it is possible to predict the chances of pregnancy in ART by measuring the degree of MMP-9 expression by using the method and kit of the present invention enhancing the efficiency of ART.
IPC 8 full level
C12Q 1/37 (2006.01); G01N 33/48 (2006.01); G01N 33/53 (2006.01)
CPC (source: EP)
C12Q 1/37 (2013.01); G01N 2333/96486 (2013.01)
Citation (search report)
- [X] NIKOLETTOS NIKOS ET AL: "Matrix metalloproteinases 2 and 9 in follicular fluids of patients undergoing controlled ovarian stimulation for ICSI/ET.", IN VIVO (ATTIKI), vol. 17, no. 2, March 2003 (2003-03-01), pages 201 - 204, XP009095270, ISSN: 0258-851X
- [X] LOTFI A S ET AL: "Identification of matrix metalloproteinases 2 and 9 in the human preovulatory follicular fluid", CLINICAL CHEMISTRY AND LABORATORY MEDICINE, vol. 39, no. Special Supplement, 2001, & 14TH IFCC-FESCC EUROPEAN CONGRESS OF CLINICAL CHEMISTRY AND LABORATORY MEDICINEAND 5TH CZECH NATION; PRAGUE, CZECHOSLOVAKIA; MAY 26-31, 2001, pages S342, XP009095269, ISSN: 1434-6621
- [X] CURRY THOMAS E JR ET AL: "The matrix metalloproteinase system: Changes, regulation, and impact throughout the ovarian and uterine reproductive cycle.", ENDOCRINE REVIEWS, vol. 24, no. 4, August 2003 (2003-08-01), pages 428 - 465, XP002467265, ISSN: 0163-769X
- See references of WO 2005093408A1
Designated contracting state (EPC)
DE FR GB
DOCDB simple family (publication)
WO 2005093408 A1 20051006; EP 1738167 A1 20070103; EP 1738167 A4 20080319; JP 2007530030 A 20071101; JP 4438865 B2 20100324
DOCDB simple family (application)
KR 2004000688 W 20040326; EP 04723855 A 20040326; JP 2007504862 A 20040326