EP 1740712 A2 20070110 - LACTOFERRIN CLEAVAGE OF NEISSERIAL PROTEINS
Title (en)
LACTOFERRIN CLEAVAGE OF NEISSERIAL PROTEINS
Title (de)
LACTOFERRINSPALTUNG VON NEISSERIA-PROTEINEN
Title (fr)
CLIVAGE PAR LA LACTOFERRINE DE PROTEINES NEISSERIALES
Publication
Application
Priority
- IB 2005001446 W 20050428
- GB 0409748 A 20040430
Abstract (en)
[origin: WO2005106009A2] Meningococcal antigens are cleaved by human lactoferrin. The invention is based on the identification of the cleavage products of this reaction, and provides a method for cleaving a neisserial polypeptide, comprising the step of mixing the polypeptide with a lactoferrin enzyme. The invention also provides polypeptides obtainable by this process (i.e. the cleavage products of the lactoferrin digestion). Proteins of particular interest are meningococcal proteins 287 and App.
IPC 8 full level
C12P 21/06 (2006.01); A61K 39/095 (2006.01); C07H 21/00 (2006.01); C07K 14/22 (2006.01)
CPC (source: EP US)
A61K 39/095 (2013.01 - EP US); C07K 14/22 (2013.01 - EP US)
Citation (search report)
See references of WO 2005106009A2
Citation (examination)
- WO 0131019 A2 20010503 - CHIRON SPA [IT], et al
- WO 02082091 A2 20021017 - SHAW ALLAN CHRISTIAN [DK], et al
- WO 02083928 A2 20021024 - AGENSYS INC [US]
- WO 02083921 A2 20021024 - AGENSYS INC [US]
- WO 0214501 A2 20020221 - AGENSYS INC [US]
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR LV MK YU
DOCDB simple family (publication)
WO 2005106009 A2 20051110; WO 2005106009 A3 20060330; EP 1740712 A2 20070110; GB 0409748 D0 20040609; US 2008193971 A1 20080814; US 8334114 B2 20121218
DOCDB simple family (application)
IB 2005001446 W 20050428; EP 05738598 A 20050428; GB 0409748 A 20040430; US 58719107 A 20071113