Global Patent Index - EP 1742911 A1

EP 1742911 A1 20070117 - 3,4-DISUBSTITUTED MALEIMIDES FOR USE AS VASCULAR DAMAGING AGENTS

Title (en)

3,4-DISUBSTITUTED MALEIMIDES FOR USE AS VASCULAR DAMAGING AGENTS

Title (de)

3,4-DISUBSTITUIERTE MALEIMIDE ZUR VERWENDUNG ALS GEFÄSSSCHÄDIGENDE MITTEL

Title (fr)

MALEIMIDES 3,4-DISUBSTITUES UTILISES EN TANT QU'AGENTS DE DEGRADATION VASCULAIRE

Publication

EP 1742911 A1 20070117 (EN)

Application

EP 05738031 A 20050422

Priority

  • GB 2005001553 W 20050422
  • EP 04291074 A 20040426
  • EP 05738031 A 20050422

Abstract (en)

[origin: WO2005102997A1] This invention relates to novel compounds of Formula (I) for use as vascular damaging agents: Formula (I) wherein R<l>, R<7>, R<8>, R<9>, AR , AR<2>, AR<3>, p, q and r are as described in the specification. The invention also relates to methods for preparing compounds of Formula (I), to their use as medicaments (including methods for the treatment of angiogenesis or disease states associated with angiogenesis) and to pharmaceutical compositions containing compounds of Formula (I).

IPC 8 full level

C07D 207/44 (2006.01); A61K 31/4015 (2006.01); A61K 31/661 (2006.01); A61P 35/00 (2006.01); C07D 207/456 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07F 9/09 (2006.01); C07F 9/12 (2006.01)

CPC (source: EP)

A61P 3/10 (2017.12); A61P 9/00 (2017.12); A61P 9/10 (2017.12); A61P 9/14 (2017.12); A61P 13/12 (2017.12); A61P 15/00 (2017.12); A61P 17/06 (2017.12); A61P 19/02 (2017.12); A61P 27/02 (2017.12); A61P 29/00 (2017.12); A61P 35/00 (2017.12); A61P 37/02 (2017.12); C07D 207/456 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01)

Citation (search report)

See references of WO 2005102997A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2005102997 A1 20051103; WO 2005102997 A8 20061123; CN 101027283 A 20070829; EP 1742911 A1 20070117; JP 2007534733 A 20071129

DOCDB simple family (application)

GB 2005001553 W 20050422; CN 200580021219 A 20050422; EP 05738031 A 20050422; JP 2007510098 A 20050422