EP 1747201 B8 20090218 - 2H OR 3H-BENZO[E]INDAZOL-1-YLE CARBAMATE DERIVATIVES, THE PREPARATION AND THERAPEUTIC USE THEREOF
Title (en)
2H OR 3H-BENZO[E]INDAZOL-1-YLE CARBAMATE DERIVATIVES, THE PREPARATION AND THERAPEUTIC USE THEREOF
Title (de)
2H- ODER 3H-BENZO[E]INDAZOL-1-YL-KARBAMAT-DERIVATE, HERSTELLUNG UND THERAPEUTISCHE VERWENDUNG
Title (fr)
DERIVES DE CARBAMATE DE 2H- OU 3H-BENZO[E]INDAZOL-1-YLE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
Publication
Application
Priority
- FR 2005001154 W 20050510
- FR 0405055 A 20040511
Abstract (en)
[origin: WO2005121099A1] The invention relates to compounds of formula (I), wherein W is an oxygen or sulphur atom, each X, X2, X3 and X4 independently represents a hydrogen or halogen atom or a cyano, C,-C6-alkyl, C,-C6-fluoralkyl, C,-C6-alkoxy, C,-C6-fluoroalkoxy group, Y is in position (N2) or (N3); when Y is in the (N2) position, Y represents a C,-C6-alkyl, C,-C6-fluoralkyl, aryl or heteroaryl group; when Y is in the (N3) position, Y represents an aryl or heteroaryl group; the aryl and heteroaryl groups are possibly substituted by one or several atoms or groups selected from halogen atoms, C,-C6-alkyl, C,-C6-alkoxy, C,-C6-alkylthio, C,-C6-alkyl-S(O)-, C,-C6-alkyl-S(0)2-, C,-C6-fluoralkyl groups; a C4-C5 position bond is double or single; each R1 et R2 independently represents an aryl, benzyl or C,-C6-alkyl group or R1 et R2 form, with a nitrogen atom carrier thereof, a heterocycle possibly substituted by one or several C1-C6-alkyl or benzyl groups in the form of a base, an acid addition salt, a hydrate or a solvate. A method for preparation and therapeutic use is also disclosed.
IPC 8 full level
C07D 231/54 (2006.01); A61K 31/416 (2006.01); C07D 231/56 (2006.01); C07D 401/12 (2006.01)
CPC (source: EP KR US)
A61K 31/416 (2013.01 - KR); A61P 3/10 (2017.12 - EP); A61P 7/02 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/04 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 9/14 (2017.12 - EP); A61P 11/00 (2017.12 - EP); A61P 13/12 (2017.12 - EP); A61P 17/00 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/02 (2017.12 - EP); A61P 25/04 (2017.12 - EP); A61P 25/08 (2017.12 - EP); A61P 25/14 (2017.12 - EP); A61P 25/16 (2017.12 - EP); A61P 25/18 (2017.12 - EP); A61P 25/20 (2017.12 - EP); A61P 25/22 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 37/06 (2017.12 - EP); A61P 39/02 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 231/54 (2013.01 - EP KR US); C07D 231/56 (2013.01 - EP US); C07D 401/12 (2013.01 - EP KR US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR LV MK YU
DOCDB simple family (publication)
FR 2870239 A1 20051118; FR 2870239 B1 20060616; AR 049090 A1 20060628; AT E411295 T1 20081015; AU 2005251982 A1 20051222; AU 2005251982 B2 20110428; BR PI0508563 A 20070814; CA 2557942 A1 20051222; CA 2557942 C 20130806; CN 100577648 C 20100106; CN 1930131 A 20070314; CR 8570 A 20071004; CY 1108710 T1 20140409; DE 602005010418 D1 20081127; DK 1747201 T3 20090216; EC SP066810 A 20061116; EP 1747201 A1 20070131; EP 1747201 B1 20081015; EP 1747201 B8 20090218; ES 2315898 T3 20090401; HK 1104288 A1 20080111; HR P20090012 T3 20090228; IL 177632 A0 20061231; IL 177632 A 20120731; JP 2007537212 A 20071220; JP 4909889 B2 20120404; KR 101165483 B1 20120713; KR 20070007796 A 20070116; MA 28372 A1 20061201; NO 20064073 L 20061106; NZ 549330 A 20100827; PL 1747201 T3 20090430; PT 1747201 E 20090119; RS 50724 B 20100831; RU 2006132325 A 20080320; RU 2379293 C2 20100120; SI 1747201 T1 20090430; TN SN06258 A1 20071203; TW 200604181 A 20060201; TW I349004 B 20110921; UA 85866 C2 20090310; US 2007105932 A1 20070510; US 2009143380 A1 20090604; US 2012108584 A1 20120503; US 7501449 B2 20090310; US 8114899 B2 20120214; US 8258168 B2 20120904; WO 2005121099 A1 20051222; ZA 200607244 B 20080430
DOCDB simple family (application)
FR 0405055 A 20040511; AR P050101865 A 20050509; AT 05770962 T 20050510; AU 2005251982 A 20050510; BR PI0508563 A 20050510; CA 2557942 A 20050510; CN 200580007686 A 20050510; CR 8570 A 20060824; CY 091100042 T 20090114; DE 602005010418 T 20050510; DK 05770962 T 20050510; EC SP066810 A 20060829; EP 05770962 A 20050510; ES 05770962 T 20050510; FR 2005001154 W 20050510; HK 07109361 A 20070828; HR P20090012 T 20090112; IL 17763206 A 20060822; JP 2007512277 A 20050510; KR 20067018339 A 20050510; MA 29294 A 20060829; NO 20064073 A 20060911; NZ 54933005 A 20050510; PL 05770962 T 20050510; PT 05770962 T 20050510; RS P20090012 A 20050510; RU 2006132325 A 20050510; SI 200530546 T 20050510; TN SN06258 A 20060815; TW 94114981 A 20050510; UA A200609699 A 20050510; US 201213348241 A 20120111; US 36053509 A 20090127; US 54929306 A 20061013; ZA 200607244 A 20060830