Global Patent Index - EP 1749829 A1

EP 1749829 A1 20070207 - JNK inhibitors

Title (en)

JNK inhibitors

Title (de)

JNK Inhibitoren

Title (fr)

JNk inhibiteurs

Publication

EP 1749829 A1 20070207 (EN)

Application

EP 06254089 A 20060803

Priority

GB 0516156 A 20050805

Abstract (en)

The present invention provides novel compounds of formula I and their use in the inhibition of c-Jun N-terminal kinases. The present invention further provides the use of these compounds in medicine, in particular in the prevention and/or treatment of neurodegenerative disorders related to apoptosis and/or inflammation.

IPC 8 full level

C07D 471/04 (2006.01); A61K 31/437 (2006.01); A61P 25/28 (2006.01)

CPC (source: EP US)

A61P 25/28 (2018.01 - EP); C07D 471/04 (2013.01 - EP US)

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  • EP 0636626 A1 19950201 - GLAXO LAB SA [FR]
  • WO 2005085244 A1 20050915 - EISAI LONDON RES LAB LTD [GB], et al
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Citation (search report)

  • [Y] WO 2004078756 A2 20040916 - EISAI LONDON RES LAB LTD [GB], et al
  • [Y] WO 03082869 A1 20031009 - EISAI LONDON RES LAB LIMTED [GB], et al
  • [Y] WO 0210137 A2 20020207 - SIGNAL PHARM INC [US], et al
  • [Y] RESNICK L ET AL: "Targeting JNK3 for the treatment of neurodegenerative disorders", DDT - DRUG DISCOVERY TODAY, ELSEVIER SCIENCE LTD, GB, vol. 9, no. 21, 1 November 2004 (2004-11-01), pages 932 - 939, XP004610030, ISSN: 1359-6446

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR MK YU

DOCDB simple family (publication)

EP 1749829 A1 20070207; EP 1749829 B1 20101103; AT E486870 T1 20101115; DE 602006017930 D1 20101216; ES 2355738 T3 20110330; GB 0516156 D0 20050914; US 2007072896 A1 20070329; US 2010035878 A1 20100211; US 7645769 B2 20100112

DOCDB simple family (application)

EP 06254089 A 20060803; AT 06254089 T 20060803; DE 602006017930 T 20060803; ES 06254089 T 20060803; GB 0516156 A 20050805; US 49933406 A 20060804; US 57395009 A 20091006