EP 1751099 A1 20070214 - CIS PYRROLIDINYL DERIVATIVES AND THEIR USES
Title (en)
CIS PYRROLIDINYL DERIVATIVES AND THEIR USES
Title (de)
CIS-PYRROLIDINYLDERIVATE UND DEREN VERWENDUNGEN
Title (fr)
DERIVES DE PYRROLIDINE CIS DISUBSTITUES ET LEURS UTILISATIONS
Publication
Application
Priority
- EP 2005005938 W 20050602
- EP 04291373 A 20040602
- EP 05755366 A 20050602
Abstract (en)
[origin: EP1604977A1] The present invention provides new cis pyrrolidinyl of the formula (I) or (II) in which:R<sub>1</sub>, R<sub>2</sub> or R<sub>3</sub> are hydrogen or a carboxy or amino protecting group; R<sub>4</sub> to R<sub>8</sub> represent hydrogen or an alkyl radical; R<sub>9</sub> represents a (R<sub>10</sub>)<sub>n</sub>(-R<sub>11</sub>)<sub>m</sub> group wherein R<sub>10</sub> is -CO-, -CS-, -O-,-S-, -SO-, -SO<sub>2</sub>-, -COO-, -CON(C<sub>n'</sub>H<sub>2n'+1</sub>)-, -N(C<sub>n'</sub>H<sub>2n'+1</sub>)CO-, -CSN(C<sub>n'</sub>H<sub>2n'+1</sub>)- ,-N(C<sub>n'</sub>H<sub>2n'+1</sub>)CS-, -N(C<sub>n'</sub>H<sub>2n'+1</sub>)-, -(C<sub>n'</sub>H<sub>2n'+1</sub>)-, aryl, and R<sub>11</sub> is a polar group,and to their use for the treatment and/or prophylaxis of a condition associated with altered glutamatergic signalling and/or functions, and/or conditions which can be affected by alteration of glutamate level or signalling
IPC 8 full level
C07D 207/16 (2006.01); A61K 31/401 (2006.01); A61P 25/00 (2006.01); C07D 207/48 (2006.01)
CPC (source: EP)
A61P 25/00 (2017.12); C07D 207/16 (2013.01); C07D 207/48 (2013.01); Y02P 20/55 (2015.11)
Citation (search report)
See references of WO 2005118534A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
EP 1604977 A1 20051214; CA 2568773 A1 20051215; EP 1751099 A1 20070214; WO 2005118534 A1 20051215
DOCDB simple family (application)
EP 04291373 A 20040602; CA 2568773 A 20050602; EP 05755366 A 20050602; EP 2005005938 W 20050602