EP 1751267 A1 20070214 - PATTERNED CELL NETWORK SUBSTRATE INTERFACE AND METHODS AND USES THEREOF
Title (en)
PATTERNED CELL NETWORK SUBSTRATE INTERFACE AND METHODS AND USES THEREOF
Title (de)
GEMUSTERTE ZELLNETZWERKSUBSTRATGRENZFLÄCHE SOWIE VERFAHREN UND VERWENDUNGEN DAVON
Title (fr)
INTERFACE DE SUBSTRAT DE RESEAU CELLULAIRE A MOTIF ET SES PROCEDES ET UTILISATIONS
Publication
Application
Priority
- CA 2005000682 W 20050505
- US 56822004 P 20040506
Abstract (en)
[origin: WO2005108547A1] There is provided herein a method and apparatus suitable for use in studying cell membrane related activities. Activities of interest include patch-clamp related studies of networks of cells on a solid substrate. Cells are grown, preferably in a patterned manner, on a substrate having microholes therein. Seals between the cells and the microholes are formed. Each microhole is attached to a channel. In many cases only one hole will be attached to a single channel, allowing examination of effects of a stimulus at a number of different points in a network of one or more cell types. This may be interest, for example, to those wishing to study interactions between neurons or neuromuscular junctions.
IPC 8 full level
C12M 1/14 (2006.01); C12M 1/34 (2006.01); C12M 3/04 (2006.01); C12N 5/00 (2006.01); C12Q 1/02 (2006.01); G01N 33/50 (2006.01)
CPC (source: EP)
C12N 5/0068 (2013.01); G01N 33/5005 (2013.01); C12N 2533/30 (2013.01); C12N 2535/10 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2005108547 A1 20051117; CA 2565855 A1 20051117; EP 1751267 A1 20070214; EP 1751267 A4 20091028
DOCDB simple family (application)
CA 2005000682 W 20050505; CA 2565855 A 20050505; EP 05741336 A 20050505