EP 1752439 B9 20120627 - Method of producing high-purity hydroxypivalaldehyde and/or dimer thereof
Title (en)
Method of producing high-purity hydroxypivalaldehyde and/or dimer thereof
Title (de)
Methode zur Herstellung von hochreinem Hydroxypivalaldehyd und/oder dessen Dimer
Title (fr)
Méthode pour la préparation d'hydroxypivalaldéhyde et/ou de son dimère à haute pureté
Publication
Application
Priority
JP 2005229171 A 20050808
Abstract (en)
[origin: EP1752439A1] The present invention provides a method of producing high-purity hydroxypivalaldehyde and/or dimer thereof, including: reacting isobutyl aldehyde with formaldehyde in a presence of a basic catalyst; distilling a low boiling point component including unreacted isobutyl aldehyde to obtain an aqueous solution; adding a diluent to the aqueous solution; cooling the aqueous solution to crystallize the hydroxypivalaldehyde and/or the dimer thereof; and subjecting the aqueous solution to a solid-liquid separation, followed by washing with an organic solvent and/or water, in which the diluent and a basic compound are added to the aqueous solution containing the hydroxypivalaldehyde and/or the dimer thereof obtained by distilling the low boiling point component off so that a concentration of the hydroxypivalaldehyde and/or the dimer becomes 5 to 23% by mass, the concentration of formaldehyde becomes 0.2 to 2.5% by mass, and a pH value becomes 5.0 or more, the solution is crystallized at a temperature of 20 to 45°C and subjected to the solid-liquid separation. In this method, handling of a high-viscosity slurry and carrying out any complicated operation such as regeneration of an ion exchange resin are not required, so the high-purity HPA and/or the dimer thereof can be obtained in high yield with an energetically advantageous manner.
IPC 8 full level
C07C 45/75 (2006.01); C07C 45/80 (2006.01); C07C 45/81 (2006.01); C07C 45/82 (2006.01); C07C 47/19 (2006.01); C07D 319/06 (2006.01)
CPC (source: EP KR US)
C07C 45/75 (2013.01 - EP US); C07C 45/80 (2013.01 - EP US); C07C 45/81 (2013.01 - EP US); C07C 45/82 (2013.01 - EP US); C07C 47/00 (2013.01 - KR); C07C 47/06 (2013.01 - KR); C07D 319/06 (2013.01 - EP US)
Designated contracting state (EPC)
DE IT SE
DOCDB simple family (publication)
EP 1752439 A1 20070214; EP 1752439 B1 20120201; EP 1752439 B9 20120627; CN 1911890 A 20070214; CN 1911890 B 20120704; KR 101330507 B1 20131115; KR 20070017908 A 20070213; SG 130108 A1 20070320; US 2007032682 A1 20070208; US 7368612 B2 20080506
DOCDB simple family (application)
EP 06118168 A 20060731; CN 200610104080 A 20060801; KR 20060073120 A 20060802; SG 2006050991 A 20060728; US 49887106 A 20060804