EP 1755677 A4 20091125 - HIGH PRESSURE SPRAY-DRY OF BIOACTIVE MATERIALS
Title (en)
HIGH PRESSURE SPRAY-DRY OF BIOACTIVE MATERIALS
Title (de)
HOCHDRUCK-SPRÜHTROCKNUNG BIOAKTIVER MATERIALIEN
Title (fr)
SECHAGE DE SUBSTANCES BIOACTIVES PAR PULVERISATION A HAUTE PRESSION
Publication
Application
Priority
- US 2005020792 W 20050613
- US 57985004 P 20040614
Abstract (en)
[origin: WO2005123131A2] This invention provides compositions and methods providing, e.g., stable powder particles containing bioactive materials. The methods include, e.g., high pressure spraying of the bioactive materials in solution or suspension, with viscosity enhancing agents, organic solvents, and/or surfactants. Formulations are provided for spraying therapeutic bioactive materials into powder particles containing amino acids and sugars. Compositions of the invention provide, e.g., high initial purity, high stability in storage, and reconstitution at high concentrations.
IPC 8 full level
A61K 39/12 (2006.01); A61K 9/14 (2006.01); A61K 9/16 (2006.01); A61K 31/715 (2006.01); A61K 39/155 (2006.01); A61K 39/215 (2006.01); A61K 45/00 (2006.01)
CPC (source: EP)
A61K 9/1688 (2013.01); A61P 31/12 (2017.12)
Citation (search report)
- [XI] WO 03087335 A2 20031023 - MEDIMMUNE VACCINES INC [US], et al
- [XP] WO 2004058156 A2 20040715 - MEDIMMUNE VACCINES INC [US], et al
- [AD] US 2003091584 A1 20030515 - YOUNG JAMES F [US], et al
- [AD] US 6531580 B1 20030311 - HUSE WILLIAM D [US], et al
- [X] BREEN E D ET AL: "Effect of moisture on the stability of a lyophilized humanized monoclonal antibody formulation", PHARMACEUTICAL RESEARCH 2001 US, vol. 18, no. 9, 2001, pages 1345 - 1353, XP002550626, ISSN: 0724-8741
- See references of WO 2005123131A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2005123131 A2 20051229; WO 2005123131 A3 20080103; AU 2005254062 A1 20051229; AU 2005254062 B2 20110217; CA 2564791 A1 20051229; EP 1755677 A2 20070228; EP 1755677 A4 20091125; JP 2008505192 A 20080221
DOCDB simple family (application)
US 2005020792 W 20050613; AU 2005254062 A 20050613; CA 2564791 A 20050613; EP 05770439 A 20050613; JP 2007527797 A 20050613