EP 1756144 A2 20070228 - ISOLATED NUCLEIC ACID MOLECULES ENCODING A NOVEL PHOSPHOPROTEIN-DARPP-32, ENCODED PROTEIN AND USES THEREOF
Title (en)
ISOLATED NUCLEIC ACID MOLECULES ENCODING A NOVEL PHOSPHOPROTEIN-DARPP-32, ENCODED PROTEIN AND USES THEREOF
Title (de)
ISOLIERTE NUKLEINSÄUREMOLEKÜLE, DIE FÜR EIN NEUES PHOSPHOPROTEIN-DARPP-32 CODIEREN, CODIERTE PROTEINE UND DEREN ANWENDUNG
Title (fr)
MOLECULES D'ACIDES NUCLEIQUES ISOLEES CODANT UNE NOUVELLE PHOSPHOPROTEINE-DARPP-32, PROTEINE CODEE ET UTILISATIONS ASSOCIEES
Publication
Application
Priority
- US 2005017356 W 20050517
- US 57263404 P 20040519
Abstract (en)
[origin: WO2005113572A2] Provided herein are novel nucleic acid and amino acids sequences of a phosphoprotein derived from a Guinea pig. Methods and compositions for modulating the phosphorylation of the novel protein in a dopaminergic signaling pathway are also provided. Compounds identified by the disclosed methods may be used to treat disorders characterized by a aberrant or dysfunctional intracellular signaling pathway regulated by DARPP-32.
IPC 8 full level
C07K 14/00 (2006.01); C07H 21/04 (2006.01); C07K 14/705 (2006.01); C07K 16/00 (2006.01); C12P 21/06 (2006.01); G01N 33/53 (2006.01)
CPC (source: EP)
C07H 21/04 (2013.01); C07K 14/70571 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2005113572 A2 20051201; WO 2005113572 A3 20060216; CA 2565014 A1 20051201; EP 1756144 A2 20070228; EP 1756144 A4 20080820
DOCDB simple family (application)
US 2005017356 W 20050517; CA 2565014 A 20050517; EP 05750662 A 20050517