EP 1758862 A1 20070307 - AMINOPYRIDINE DERIVATIVES AS SELECTIVE DOPAMINE D3 AGONISTS
Title (en)
AMINOPYRIDINE DERIVATIVES AS SELECTIVE DOPAMINE D3 AGONISTS
Title (de)
AMINOPYRIDINDERIVATE ALS SELEKTIVE DOPAMIN-D3-AGONISTEN
Title (fr)
DERIVES D'AMINOPYRIDINE UTILISES COMME AGONISTES SELECTIFS DE LA DOPAMINE D3
Publication
Application
Priority
- IB 2005001554 W 20050517
- GB 0411891 A 20040527
- GB 0412463 A 20040603
Abstract (en)
[origin: WO2005115985A1] The present invention provides for compounds of formula (I) which are a class of dopamine agonists, more particularly a class of agonists that are selective for D3 over D2. These compounds are useful for the treatment and/or prevention of sexual dysfunction, for example female sexual dysfunction (FSD), in particular female sexual arousal disorder (FSAD), hypoactive sexual desire disorder (HSDD; lack of interest in sex), female orgasmic disorder (FOD; inability to achieve orgasm); and male sexual dysfunction, in particular male erectile dysfunction (MED). Male sexual dysfunction as referred to herein is meant to include ejaculatory disorders such as premature ejaculation, anorgasmia (inability to achieve orgasm) or desire disorders such as hypoactive sexual desire disorder (HSDD; lack of interest in sex). These compounds are also useful in treating neuropsychiatric disorders and neurodegenerative disorders.
IPC 8 full level
C07D 213/73 (2006.01); A61K 31/44 (2006.01); A61K 31/4427 (2006.01); A61K 31/5377 (2006.01); A61P 15/00 (2006.01); A61P 25/00 (2006.01); C07D 401/04 (2006.01); C07D 413/04 (2006.01); C07D 417/04 (2006.01)
CPC (source: EP)
A61P 3/04 (2017.12); A61P 3/06 (2017.12); A61P 3/10 (2017.12); A61P 5/00 (2017.12); A61P 9/10 (2017.12); A61P 9/12 (2017.12); A61P 15/00 (2017.12); A61P 15/08 (2017.12); A61P 15/10 (2017.12); A61P 17/02 (2017.12); A61P 21/04 (2017.12); A61P 25/00 (2017.12); A61P 25/06 (2017.12); A61P 25/14 (2017.12); A61P 25/16 (2017.12); A61P 25/18 (2017.12); A61P 25/22 (2017.12); A61P 25/24 (2017.12); A61P 25/28 (2017.12); A61P 29/00 (2017.12); A61P 43/00 (2017.12); C07D 213/73 (2013.01); C07D 401/04 (2013.01); C07D 413/04 (2013.01); C07D 417/04 (2013.01)
Citation (search report)
See references of WO 2005115985A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR LV MK YU
DOCDB simple family (publication)
WO 2005115985 A1 20051208; AP 2006003824 A0 20061231; AR 049548 A1 20060816; AU 2005247699 A1 20051208; BR PI0511571 A 20080102; CA 2567935 A1 20051208; CA 2567935 C 20091027; EA 200601982 A1 20070427; EC SP067029 A 20061229; EP 1758862 A1 20070307; GT 200500125 A 20060110; IL 179314 A0 20070308; JP 2008500331 A 20080110; JP 4198183 B2 20081217; MA 28607 B1 20070502; MX PA06013786 A 20070125; NL 1029139 A1 20051130; NL 1029139 C2 20060619; NO 20065326 L 20061219; PA 8635101 A1 20060516; PE 20060366 A1 20060515; SV 2005002129 A 20051213; TW 200609216 A 20060316; UY 28925 A1 20051230
DOCDB simple family (application)
IB 2005001554 W 20050517; AP 2006003824 A 20050517; AR P050102169 A 20050526; AU 2005247699 A 20050517; BR PI0511571 A 20050517; CA 2567935 A 20050517; EA 200601982 A 20050517; EC SP067029 A 20061127; EP 05747191 A 20050517; GT 200500125 A 20050524; IL 17931406 A 20061115; JP 2007514200 A 20050517; MA 29488 A 20061127; MX PA06013786 A 20050517; NL 1029139 A 20050526; NO 20065326 A 20061120; PA 8635101 A 20050526; PE 2005000583 A 20050525; SV 2005002129 A 20050527; TW 94117274 A 20050526; UY 28925 A 20050526