EP 1759020 A4 20080416 - ACACS AS MODIFIERS OF THE IGF PATHWAY AND METHODS OF USE
Title (en)
ACACS AS MODIFIERS OF THE IGF PATHWAY AND METHODS OF USE
Title (de)
ACACS ALS MODIFIKATOREN DES IGF-WEGES UND VERWENDUNGSVERFAHREN
Title (fr)
ACACS UTILISES COMME GENES MODIFICATEURS DE LA VOIE IGF ET LEURS PROCEDES D'UTILISATION
Publication
Application
Priority
- US 2005021682 W 20050620
- US 58168904 P 20040621
Abstract (en)
[origin: WO2006009933A2] Human CDK9 genes are identified as modulators of the IGF pathway, and thus are therapeutic targets for disorders associated with defective IGF function. Methods for identifying modulators of IGF, comprising screening for agents that modulate the activity of CDK9 are provided.
IPC 8 full level
G01N 33/574 (2006.01); G01N 33/50 (2006.01)
CPC (source: EP US)
A61P 31/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C12Q 1/485 (2013.01 - EP US); C12Q 1/6886 (2013.01 - EP US); G01N 33/573 (2013.01 - EP US); G01N 33/57438 (2013.01 - EP US); G01N 33/6872 (2013.01 - EP US); C12Q 2600/136 (2013.01 - EP US); C12Q 2600/16 (2013.01 - EP US); G01N 2500/00 (2013.01 - EP US); Y10T 436/143333 (2015.01 - EP US)
Citation (search report)
- [X] WO 03100008 A2 20031204 - SCHERING CORP [US], et al
- [X] WO 02100897 A2 20021219 - CENTRE NAT RECH SCIENT [FR], et al
- [X] US 5759837 A 19980602 - KUHAJDA FRANCIS P [US], et al
- [X] WO 02100896 A2 20021219 - CENTRE NAT RECH SCIENT [FR], et al
- [X] EDER I E ET AL: "Genes differentially expressed in prostate cancer", BJU INTERNATIONAL 200405 GB, vol. 93, no. 8, May 2004 (2004-05-01), pages 1151 - 1155, XP008089312, ISSN: 1464-4096
- [A] MAXWELL PATRICK H ET AL: "Activation of the HIF pathway in cancer", CURRENT OPINION IN GENETICS AND DEVELOPMENT, vol. 11, no. 3, June 2001 (2001-06-01), pages 293 - 299, XP008089299, ISSN: 0959-437X
- See references of WO 2006009962A2
Citation (examination)
ZHAO H ET AL: "PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells", ONCOGENE, NATURE PUBLISHING GROUP, GB, vol. 23, no. 3, 22 January 2004 (2004-01-22), pages 786 - 794, XP008083876, ISSN: 0950-9232, DOI: 10.1038/SJ.ONC.1207162
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR LV MK YU
DOCDB simple family (publication)
WO 2006009933 A2 20060126; WO 2006009933 A3 20061116; AU 2005265195 A1 20060126; AU 2005265212 A1 20060126; AU 2005265224 A1 20060126; AU 2005265224 B2 20110929; CA 2567980 A1 20060126; CA 2568012 A1 20060126; CA 2569046 A1 20060126; EP 1758994 A2 20070307; EP 1758994 A4 20080416; EP 1759020 A2 20070307; EP 1759020 A4 20080416; EP 1759206 A2 20070307; EP 1759206 A4 20080416; JP 2008503236 A 20080207; JP 2008503239 A 20080207; JP 2008504024 A 20080214; US 2008095763 A1 20080424; US 2009022737 A1 20090122; US 2009053239 A1 20090226; US 7927872 B2 20110419; US 8758994 B2 20140624; WO 2006009947 A2 20060126; WO 2006009947 A3 20061228; WO 2006009950 A2 20060126; WO 2006009950 A3 20060323; WO 2006009962 A2 20060126; WO 2006009962 A3 20070531
DOCDB simple family (application)
US 2005021630 W 20050620; AU 2005265195 A 20050620; AU 2005265212 A 20050620; AU 2005265224 A 20050620; CA 2567980 A 20050620; CA 2568012 A 20050620; CA 2569046 A 20050620; EP 05762484 A 20050620; EP 05766575 A 20050620; EP 05789866 A 20050620; JP 2007518150 A 20050620; JP 2007518154 A 20050620; JP 2007518161 A 20050620; US 2005021650 W 20050620; US 2005021653 W 20050620; US 2005021682 W 20050620; US 62848705 A 20050620; US 62857505 A 20050620; US 62863605 A 20050620