Title (en)

ESSENTIAL FATTY ACIDS IN THE PREVENTION AND/OR TREATMENT OF DEPRESSION IN PATIENTS WITH CORONARY HEART OR ARTERY DISEASE

Title (de)

ESSENTIELLE FETTSÄUREN ZUR VORBEUGUNG UND/ODER BEHANDLUNG VON DEPRESSION BEI PATIENTEN MIT KORONARER HERZ- ODER ARTERIENKRANKHEIT

Title (fr)

ACIDES GRAS ESSENTIELS POUR LA PRÉVENTION ET/OU LE TRAITMENT DES DÉPRESSIONS CHEZ DES PATIENTS PRÉSENTANT DES MALADIES CORONAIRES DU COEUR

Publication

EP 1765319 A1 20070328 (EN)

Application

EP 05779398 A 20050415

Priority

• EP 2005004031 W 20050415
• EP 04101578 A 20040416
• EP 05779398 A 20050415

Abstract (en)

[origin: WO2005110393A1] This invention concerns the use of a pharmaceutical composition containing essential fatty acid ethyl esters originating from fish oils, in particular as a high concentration mixture of ethyl esters of (2O:5omega 3) eicosapentaenoic acid (EPA) and (22:6omega (3) docosahexaenoic acid (DHA) in the prevention and/or treatment of depression in patients with cardiovascular disease, such as coronary heart and/or coronary artery or vascular disease.

IPC 8 full level

A61K 31/19 (2006.01); A61K 31/202 (2006.01); A61K 31/21 (2006.01); A61P 9/00 (2006.01); A61P 25/24 (2006.01)

CPC (source: EP)

A61K 9/4858 (2013.01); A61K 9/4866 (2013.01); A61K 31/201 (2013.01); A61P 9/00 (2017.12); A61P 9/10 (2017.12); A61P 25/24 (2017.12)

Citation (search report)

See references of WO 2005110393A1

Citation (examination)

• WO 9848788 A1 19981105 - SCOTIA HOLDINGS PLC [GB], et al
• WO 02096408 A1 20021205 - LAXDALE LTD [GB], et al
• RUPP, H. ET AL.: "Risk Stratification by the EPA+DHA Level and the EPA/AA RatioFocus on Anti-Inflammatory and Antiarrhythmogenic Effects of Long-Chain Omega-3 Fatty Acids", HERZ, vol. 29, no. 7, 2004, pages 673 - 685, DOI: 10.1007/s00059-004-2602-4
• SPIEKER, L. ET AL.: "Pathophysiologische Herz-Kreislauf-Veränderungen bei Stress und Depression", THERAPEUTISCHE UMSCHAU, vol. 60, no. 11, 2003, pages 667 - 672, DOI: 10.1024/0040-5930.60.11.667
• MARANGELL, L. ET AL.: "A Double-Blind, Placebo-Controlled Study of the Omega-3 Fatty Acid Docosahexaenoic Acid in the Treatment of Major Depression", AM J PSYCHIATRY, vol. 160, 5 May 2003 (2003-05-05), pages 996 - 998
• LAWSON, L. ET AL.: "HUMAN ABSORPTION OF FISH OIL FATTY ACIDS AS TRIGLYCEROLS, FREE ACIDS OR ETHYL ESTERS", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 152, no. 1, 15 April 1988 (1988-04-15), pages 328 - 335
• BOUSTANI, S. ET AL.: "ENTERAL ABSORPTION IN MAN OF EICOPENTAENOIC ACID IN DIFFERENT CHEMICAL FORMS", LIPIDS, vol. 22, no. 10, 1987, pages 711 - 714
• IKEDA, I. ET AL.: "LYMPHATIC TRANSPORT OF EICOSAPENTAENOIC ACID AND DOCOSAHEXAENOIC ACIDS AS TRIGLYCERIDE, ETHYL ESTER AND FREE ACID, AND THEIR EFFECT ON CHOLESTEROL TRANSPORT IN RATS", LIFE SCIENCE, vol. 52, no. 16, 1993, pages 1371 - 1379
• KOZAK, M. ET AL.: "CIRCADIAN VARIATIONS IN THE OCCURRENCE OF VENTRICULAR TACHYARRHYTHMIAS IN PATIENTS WITH IMPLANATABLE CARDIOVERTER DEFRIBRILLATORS", PACE, vol. 26, March 2003 (2003-03-01), pages 731 - 735
• "ROTE LISTE", November 2007, article "OMACOR"
• "HUNNIUS PHARMAZEUTISCHES WÖRTERBUCH", 1993, pages: 544

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR LV MK YU

DOCDB simple family (publication)

WO 2005110393 A1 20051124; AU 2005244483 A1 20051124; AU 2005244483 B2 20110609; BR PI0509878 A 20071016; CA 2504280 A1 20051016; CN 1942180 A 20070404; EP 1765319 A1 20070328; IL 178300 A0 20070211; JP 2007532605 A 20071115; MX 291518 B 20111031; MX PA06011940 A 20061215; RU 2006140277 A 20080527; RU 2387448 C2 20100427; UA 94693 C2 20110610; ZA 200607794 B 20080528

DOCDB simple family (application)

EP 2005004031 W 20050415; AU 2005244483 A 20050415; BR PI0509878 A 20050415; CA 2504280 A 20050415; CN 200580011428 A 20050415; EP 05779398 A 20050415; IL 17830006 A 20060926; JP 2007507767 A 20050415; MX PA06011940 A 20050415; RU 2006140277 A 20050415; UA A200611798 A 20050415; ZA 200607794 A 20050415