EP 1768676 A1 20070404 - USE OF COMPOUNDS CONTAINING THIOL GROUPS AS AN EFFLUX PUMP INHIBITOR
Title (en)
USE OF COMPOUNDS CONTAINING THIOL GROUPS AS AN EFFLUX PUMP INHIBITOR
Title (de)
VERWENDUNG VON THIOLGRUPPEN-HALTIGEN VERBINDUNGEN ALS EFFLUX-PUMPEN-HEMMER
Title (fr)
UTILISATION DE COMPOSES CONTENANT DES GROUPES THIOL EN TANT QU'INHIBITEURS DE POMPES D'EFFLUX
Publication
Application
Priority
- EP 2005053395 W 20050714
- AT 12502004 A 20040722
Abstract (en)
[origin: WO2006008270A1] The non-invasive administration of many active ingredients fails with efflux pumps which sharply reduce the active ingredient resorption on mucous membranes. According to the invention, the active ingredient resorption on mucous membranes can be drastically improved by using dosages containing glutathione and/or compounds comprising numerous thiol groups, in addition to the active ingredient(s). Forms of administration such as matrix tablets, capsules, eye drops, or microparticles, containing the cited combination of active ingredients and auxiliary substances, can be used.
IPC 8 full level
A61K 31/7048 (2006.01); A61K 31/716 (2006.01); A61K 31/717 (2006.01); A61K 31/795 (2006.01); A61K 38/03 (2006.01); A61K 38/06 (2006.01); A61K 38/13 (2006.01); A61K 38/33 (2006.01); A61K 45/06 (2006.01)
CPC (source: EP US)
A61K 31/7048 (2013.01 - EP US); A61K 31/716 (2013.01 - EP US); A61K 31/717 (2013.01 - EP US); A61K 31/795 (2013.01 - EP US); A61K 38/03 (2013.01 - EP US); A61K 38/063 (2013.01 - EP US); A61K 38/13 (2013.01 - EP US); A61K 38/33 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61P 27/02 (2017.12 - EP); A61P 31/04 (2017.12 - EP)
Citation (search report)
See references of WO 2006008270A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2006008270 A1 20060126; AU 2005263729 A1 20060126; AU 2005263729 B2 20110106; CA 2574232 A1 20060126; CN 101035547 A 20070912; EP 1768676 A1 20070404; JP 2008506750 A 20080306; US 2008200563 A1 20080821
DOCDB simple family (application)
EP 2005053395 W 20050714; AU 2005263729 A 20050714; CA 2574232 A 20050714; CN 200580024231 A 20050714; EP 05771836 A 20050714; JP 2007521944 A 20050714; US 63286805 A 20050714