EP 1774046 A4 20100915 - NOVEL NUCLEOTIDE AND AMINO ACID SEQUENCES AND ASSAYS AND METHODS OF USE THEREOF FOR DIAGNOSIS OF LUNG CANCER

Title (en)

NOVEL NUCLEOTIDE AND AMINO ACID SEQUENCES AND ASSAYS AND METHODS OF USE THEREOF FOR DIAGNOSIS OF LUNG CANCER

Title (de)

NEUE NUKLEOTID- UND AMINOSÄURESEQUENZEN SOWIE ASSAYS UND VERFAHREN ZU DEREN VERWENDUNG BEI DER DIAGNOSE VON LUNGENKREBS

Title (fr)

NOUVELLES SEQUENCES D'AMINOACIDES ET DE NUCLEOTIDES, ET DOSAGES ET METHODES D'UTILISATION AFFERENTES DANS LE DIAGNOSTIC DU CANCER DU POUMON

Publication

EP 1774046 A4 20100915 (EN)

Application

EP 05857765 A 20050127

Priority

IB 2005004037 W 20050127
US 53912804 P 20040127
US 53912904 P 20040127
US 58981504 P 20040722
US 60730704 P 20040907
US 62091604 P 20041022
US 62091704 P 20041022
US 62087404 P 20041022
US 62092404 P 20041022
US 62097404 P 20041022
US 62085304 P 20041022
US 62065604 P 20041022
US 62091804 P 20041022
US 62100404 P 20041022
US 62086804 P 20041022
US 62067704 P 20041022
US 62097504 P 20041022
US 62113104 P 20041025
US 62105304 P 20041025
US 62812304 P 20041117
US 62810104 P 20041117
US 62813404 P 20041117
US 62811104 P 20041117
US 62811204 P 20041117
US 62814504 P 20041117
US 62818904 P 20041117
US 62816704 P 20041117
US 62815604 P 20041117
US 62825104 P 20041117
US 62817804 P 20041117
US 63407504 P 20041208
US 5172005 A 20050127

Abstract (en)

[origin: WO2006131783A2] Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of lung cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between lung cancer and non-cancerous states.

IPC 8 full level

G01N 33/48 (2006.01); G06F 19/00 (2006.01)

CPC (source: EP)

C12Q 1/6886 (2013.01); C12Q 2600/112 (2013.01)

Citation (search report)

[X] DATABASE GSP [online] 22 August 2002 (2002-08-22), "Human ovarian antigen HOPKL1", XP002594292, Database accession no. ABP41861
[X] DATABASE GSP [online] 12 July 2003 (2003-07-12), "Breast Cancer associated protein sequence SEq ID NO: 298", XP002594101, Database accession no. ABR47531
[X] DATABASE EMBASE [online] ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL; 7 September 2002 (2002-09-07), ISOGAI T., YAMAMOTO J.: "Homosapiens cDNA fis, clone PLACE1005783, highly similar to STROMELYSIN-3 precursor", XP002594102, Database accession no. EM_HUM:AK075448
[X] DATABASE EMBL [online] 26 January 2001 (2001-01-26), "MR3-GN0153-101100-014-a10 GN0153 Homo sapiens cDNA, mRNA sequence.", XP002594103, retrieved from EBI accession no. EMBL:BF999015 Database accession no. BF999015
[A] GALL A-L ET AL: "Crystal structure of the stromelysin-3 (MMP-11) catalytic domain complexed with a phosphinic inhibitor mimicking the transition-state", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB LNKD- DOI:10.1006/JMBI.2001.4493, vol. 307, no. 2, 23 March 2001 (2001-03-23), pages 577 - 586, XP004466039, ISSN: 0022-2836
[A] CHO NAM HOON ET AL: "MMP expression profiling in recurred stage IB lung cancer.", ONCOGENE, vol. 23, no. 3, 22 January 2004 (2004-01-22), pages 845 - 851, XP002594104, ISSN: 0950-9232
[A] DELEBECQ T J ET AL: "Overexpression level of stromelysin 3 is related to the lymph node involvement in non-small cell lung cancer.", CLINICAL CANCER RESEARCH : AN OFFICIAL JOURNAL OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH MAR 2000 LNKD- PUBMED:10741738, vol. 6, no. 3, March 2000 (2000-03-01), pages 1086 - 1092, XP002594105, ISSN: 1078-0432 & WO 03004989 A2 20030116 - MILLENIUM PHARMACEUTICALS INC [US], et al
See references of WO 2006131783A2

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2006131783 A2 20061214; WO 2006131783 A3 20090827; AU 2005320352 A1 20060831; AU 2005320352 A2 20060831; AU 2005320352 A8 20090430; CA 2555509 A1 20050727; EP 1774046 A2 20070418; EP 1774046 A4 20100915; JP 2008507261 A 20080313

DOCDB simple family (application)

IB 2005004037 W 20050127; AU 2005320352 A 20050127; CA 2555509 A 20050127; EP 05857765 A 20050127; JP 2007519922 A 20050127