EP 1776113 A1 20070425 - PHARMACEUTICAL FORMULATION BASED ON ANTIBIOTIC IN MICROCAPSULE FORM
Title (en)
PHARMACEUTICAL FORMULATION BASED ON ANTIBIOTIC IN MICROCAPSULE FORM
Title (de)
PHARMAZEUTISCHE FORMULIERUNG AUF BASIS EINES ANTIBIOTIKUMS IN MIKROKAPSELFORM
Title (fr)
FORMULATION PHARMACEUTIQUE A BASE D'ANTIBIOTIQUE SOUS FORME MICROCAPSULAIRE
Publication
Application
Priority
- FR 2005050366 W 20050525
- FR 0451353 A 20040628
Abstract (en)
[origin: TW200602090A] The invention relates to oral antibiotic drugs. The object of the invention is to limit or even stop the increase in antibiotic resistance without sacrificing the requirements of (a) increased efficacy of oral antibiotics, particularly for pediatric applications, (b) tolerance, (c) broad spectra of activity, and (d) good patient compliance. This object is achieved by the invention, which proposes the use of modified-release microcapsules, comprising a core that contains at least one active principle AP1 formed of at least one antibiotic, and a coating for said core that governs the modified release of said active principle, for the manufacture of a drinkable or orally dispersible antibiotic pharmaceutical formulation that makes it possible to limit the increase in the antibiotic resistance of the target germs, this formulation being: - capable of administration in one or two, preferably two, dosage units per day, - and definable as follows, relative to an immediate-release oral formulation (IRF*) comprising at least one active principle AP1, and for the same dose D of AP1 as IRF*: Tmic>T*mic of IRF*
IPC 8 full level
A61K 31/43 (2006.01); A61K 9/50 (2006.01)
CPC (source: EP US)
A61K 9/5047 (2013.01 - EP US); A61K 9/5084 (2013.01 - EP US); A61K 31/43 (2013.01 - EP US); A61P 31/00 (2017.12 - EP); A61P 31/04 (2017.12 - EP)
Citation (search report)
See references of WO 2006010868A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
FR 2872044 A1 20051230; FR 2872044 B1 20070629; CA 2571045 A1 20060202; CN 101014340 A 20070808; EP 1776113 A1 20070425; JP 2008504352 A 20080214; TW 200602090 A 20060116; US 2008026056 A1 20080131; WO 2006010868 A1 20060202
DOCDB simple family (application)
FR 0451353 A 20040628; CA 2571045 A 20050525; CN 200580021439 A 20050525; EP 05766691 A 20050525; FR 2005050366 W 20050525; JP 2007518654 A 20050525; TW 94117656 A 20050530; US 63103005 A 20050525