EP 1781269 A2 20070509 - IgE-RETARGETING, FUNCTION-ALTERING MOLECULES (ERFAM) FOR TREATMENT OF ALLERGIC DISEASES
Title (en)
IgE-RETARGETING, FUNCTION-ALTERING MOLECULES (ERFAM) FOR TREATMENT OF ALLERGIC DISEASES
Title (de)
IgE-RETARGETING FUNKTIONSÄNDERNDE MOLEKÜLE (ERFAM) FÜR DIE BEHANDLUNG VON ALLERGISCHEN ERKRANKUNGEN
Title (fr)
MOLECULES DE RECIBLAGE D'IgE, ALTERANT LES FONCTIONS (ERFAM), POUR TRAITER DES MALADIES ALLERGIQUES
Publication
Application
Priority
- IB 2005003950 W 20050519
- US 57282104 P 20040520
Abstract (en)
[origin: WO2006048781A2] The invention provides an IgE-Retargeting, Function-Altering Molecules (ERFAM) construct of the formula A'-B', wherein A' represents a moiety that binds an IgE and B' represents a moiety that binds an inhibitory receptor; or a construct of the formula A'-X-B', wherein A' represents a moiety that binds an IgE, X represents a linker moiety, B' represents a moiety that binds an inhibitory receptor. Also provided are their methods of use in treating IgE-related disorders, e.g., allergy.
IPC 8 full level
C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61P 37/00 (2006.01); C07K 16/42 (2006.01)
CPC (source: EP)
A61P 37/00 (2017.12); A61P 37/08 (2017.12); C07K 16/2803 (2013.01); C07K 16/283 (2013.01); C07K 16/4291 (2013.01); C12N 15/115 (2013.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01); C07K 2317/34 (2013.01); C07K 2317/55 (2013.01); C12N 2310/16 (2013.01); C12N 2310/3513 (2013.01)
Citation (search report)
See references of WO 2006048781A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR LV MK YU
DOCDB simple family (publication)
WO 2006048781 A2 20060511; WO 2006048781 A3 20080214; AU 2005300261 A1 20060511; CA 2566535 A1 20060511; CN 101522714 A 20090902; EP 1781269 A2 20070509; JP 2008513351 A 20080501
DOCDB simple family (application)
IB 2005003950 W 20050519; AU 2005300261 A 20050519; CA 2566535 A 20050519; CN 200580023542 A 20050519; EP 05821176 A 20050519; JP 2007517532 A 20050519